hiv/aids-medicines supplier

What is Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) are used to slow down the progression of HIV infection which can lead to AIDS and other related illnesses. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) do not cure AIDS or destroy the HIV virus, but rather delay any further damage to the immune system by stopping production of new viruses.

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) is taken with other antiretroviral medications to treat adults infected with HIV-1. A single pill is the equivalent of 300mg of lamivudine IP and 600mg of abacavir. At least one other anti-HIV medication must be co-administered with Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) to effectively prevent HIV from progressing to AIDS.

Used For Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) is a combination of two medications, abacavir and lamivudine which belong to a class of medicines called antiretrovirals. They are used together with other antiretrovirals to slow down the progression of HIV infection (human immunodeficiency virus), which can lead to AIDS (Acquired Immune Deficiency Syndrome) and other related illnesses for example, AIDS – related Complex or ARC.

Dosing & Administration Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)

The recommended dose of Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) for adults is one pill daily along with other antiretroviral medications. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) may be taken with or without food.

Drug Interactions Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)

Ethanol may hinder the kidneys' ability to eliminate abacavir. Zalcitabine cannot be coadministered with Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) because zalcitabine and lamivudine inhibit one another.

Work Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

The two medications abacavir and lamivudine combined together help prevent HIV from reproducing. The HIV virus is responsible for acquired immune deficiency syndrome as HIV infection destroys CD4 (T) cells, which are important to the body’s immune system. The immune system is what helps fight infections. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) do not cure AIDS or destroy the HIV virus, but rather delay further damage to the immune system by stopping production of new viruses. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) do not reduce the risk of passing infection to others. It is important that you continue to take precautions to prevent this from happening as the HIV virus can still be passed on by sexual activity or by contamination with infected blood.

Overdose Warning Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)

The effects of an Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) overdose are at this point unknown. Do not take more than the recommended dose

Side effects of Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) can cause some side effects. If they do occur and some may be serious, seek medical advice from your health professional as you may require medical attention. As Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) contain both abacavir and lamivudine, the side effects reported for each of these have been combined. It has been reported that the most common side effects which could affect at least one to ten in every 100 people include nausea, vomiting, diarrhoea, upper abdominal pain, headache, high temperature, lethargy, fatigue, loss of appetite, hair loss, joint and muscle pain, abacavir hypersensitivity and skin rash. Less common side effects which could affect less than 1 in every 100 people include increased liver enzyme production, anaemia (low red blood cell count), neutropenia (low white blood cell count), reduced number of blood cells important for blood clotting.

You may show symptoms of tiredness or breathlessness if the production of red blood cells is reduced. A reduction in your white blood cell count can make you more susceptible to infection.

Rare side effects which could affect less than one in every 1000 people are breakdown of muscle tissue, increases of an enzyme called amylase and inflammation of the pancreas. Very rare side effects which could affect less than one in every 10,000 people are serious skin reactions and severe anaemia. It has been documented that any changes in fat distribution are associated with antiretroviral medications, which may include loss of fat from legs, arms and face and also increased fat in the abdomen and other internal organs, breasts and the back of the neck. Changes in the amount of fatty substances and glucose in the blood have also been reported. Within the first few weeks of commencing treatment with anti-HIV medicines, some people and in particular those that have been HIV positive for some time, may develop inflammatory reactions for example, pain, redness, swelling and high temperature which may resemble an infection and may be severe. If you notice any changes in your health after commencing HIV treatment or become concerned with any new symptoms, then it is advisable you discuss this with your medical professional immediately. If you experience any of the following, call your doctor immediately. Lactic Acidosis – if you become very sick with accelerated breathing, you may have a condition known as this. High acid levels in the blood can cause rapid breathing and be life threatening. This is more common in women than men. If you experience allergic reactions soon after starting Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) medication, for example wheezing, any swelling of the lips/mouth, difficulty in breathing, hay fever, hives or fainting then call your doctor immediately. Like all medications, there may be other side effects that occur in some people that are not listed or some side effects that are not yet known.

Efavir (Efavirenz 200mg Tablets)

The main active ingredient is Efavir (Efavirenz 200mg Tablets), Non-nucleoside Reverse Transcriptase Inhibitors, used actively against HIV or AIDS virus. This medicine is quite effective to reduce the discomfort and severity of AIDS and it is a very popular part of antiretroviral therapy.

Efavir (Efavirenz 200mg Tablets) used for?

Efavir (Efavirenz 200mg Tablets) (also known as Sustiva) are used with other HIV medications as part of combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection in adults and children three years of age or older.  Efavir (Efavirenz 200mg Tablets) must not be used alone as the virus can develop resistance if used as monotherapy and Efavir (Efavirenz 200mg Tablets) is, therefore, combined with two other drugs that have a different mechanism of action.  This treatment regime is known as highly active antiretroviral therapy (HAART) and is designed to minimise the ability of the virus to multiply and help prevent development of viral resistance to treatment.  HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful).  Also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS).  Efavir (Efavirenz 200mg Tablets) slows down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level (reduces viral load) and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression. 

Efavir (Efavirenz 200mg Tablets) work?

Efavir (Efavirenz 200mg Tablets) (also known as Sustiva) contain efavirenz, a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), which is only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV).  It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate.  Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate.  Efavirenz in Efavir (Efavirenz 200mg Tablets) acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA.  This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus).  Efavir (Efavirenz 200mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others. 

Dosage form and strengths:

This drug is available in the tablet form in the following strength on our website:

1. Efavirenz tablets 200 mg
2. Efavirenz tablets 600 mg

Efavir (Efavirenz 200mg Tablets) Dosage:

How much to take the drug?

The dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly. The usual dose is one 200/600 mg tablet once in a day, although the dose strength will depend upon the condition of the patient.

How to take the drug?

Swallow the tablet with one glass full of water. Do not break the tablet. Take the drug exactly as directed. Take the medicine on empty stomach, or as directed by your doctor. HIV is usually treated with a combination of drugs. Always take the prescribed drugs as directed by your doctor in combination with other HIV drugs. The drug comes with a warning card that lists the symptoms of allergic reactions. Read this card and carry if always with you. Take the tablet at the same time each day, so as to avoid forgetting the dose. This should become a habit for you to take the tablet until the doctor tells you to stop the drug.

For how long to take it?

This drug controls the multiplication of HIV but does not cure the problem. Take the drugs as long as your doctor recommends you to take it. .

Overdose:

If you feel any alarming symptoms then immediately consult the doctor about this drug and its possible side effects of over dosage. If the situation worsens then visit the nearest healthcare center or call the emergency helpline number.

Miss dose:

In case you forget to take the dose, skip the dose and take the next dose on the recommended time period. Do not double up the dose for the missed one.

Efavir (Efavirenz 200mg Tablets) Side effects:

Efavir (Efavirenz 200mg Tablets) can lead to severe psychiatric problems such as severe depression, confusion, suicidal thoughts, aggression, extreme fear, hallucinations, or unusual behavior. Inform you doctor right away if you get any of these side effects while taking Efavir (Efavirenz 200mg Tablets), even if you have had them before. Also, tell your doctor as soon as possible if you notice any of the following:

• Diarrhea
• Fat gain or loss
• Muscle pain
• Unexplained weight loss
• Seizures
• Headache
• Joint pain
• Vision changes
• Skin rashes, hives and itching
• Tiredness

In such cases you must go for immediate medical help. Do not get alarmed by the list. You may /may not experience all of them. Tell your doctor immediately in the above situations.

Efavir (Efavirenz 200mg Tablets) Warning:

Things to remember:

1. You must use a proper barrier contraceptive method while taking Efavir (Efavirenz 200mg Tablets) and for at least 12 weeks following the end of you treatment
2. Discuss them with your doctor and clear all doubts which you may have about this drug
3. Store this medication in a cool and dry place
4. Never start a new medication without consulting your doctor first

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contains two active ingredients Lopinavir and Ritonavir.  It is mainly used to treat people with human immunodeficiency virus (HIV) infection. You can buy Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) online also.

This medication is an HIV-1 protease inhibitor which is used in combination with other antiretroviral agents for HIV-1 infection treatment in adults and paediatric patients 14 days and older.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) used for?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over and children over 6 months. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other medications that have a different mechanism of action to the components in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) work?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contain lopinavir and ritonavir, which are both inhibitors of HIV protease and are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). Retroviruses convert RNA to DNA, by the action of the viral-specific enzyme reverse transcriptase (RT). The viral DNA is then integrated into the DNA of infected immune cells so that the virus can replicate. Most of the antiviral activity of Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is due to lopinavir, which is a potent inhibitor of HIV protease, and prevents cleavage of the Gag-Pol polyprotein, an important protein in the development of active virus. The viral protease enzyme cleaves (breaks down) the Gag-Pol polyprotein during final stages of the replication cycle so that fully active mature virus can be released to infect new cells. Inhibition of protease cleavage by Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) results in the production of immature, non-infectious viral particles. Ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is included in the combination not as a protease inhibitor but because it inhibits the CYP3A-mediated metabolism (breakdown in the liver) of lopinavir, thereby increasing the plasma levels of lopinavir so that lopinavir can be used at a lower dose. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other retrovirals that have a different mechanism of action, like emtricitabine and tenofovir, both nucleoside reverse transcriptase inhibitor (NRTI) that work by blocking the action of RT, inhibiting viral replication. The combined action of lopinavir and ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), in conjunction with other retroviral drugs, inhibits the production of active HIV so that the viral load (amount of virus) is reduced. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) Side Effects

• The most common Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) side effects occurring in 5% or more of the patients undergoing treatment with this medication were diarrhea, nausea, abdominal pain, asthenia, vomiting, headache, and dyspepsia.
• The most commonly reported Generic Kaletra side effects of moderate severity that are thought to be drug related are: abdominal pain, abnormal stools (bowel movements), diarrhea, feeling tired, headache, and nausea. Children taking this medicine may sometimes get a skin rash.
• Blood tests in patients taking this medicine may show possible liver problems. People with liver disease such as Hepatitis B and Hepatitis C who take this medicine may have worsening liver disease. Liver problems including death have occurred in patients taking this medicine. In studies, it is unclear if this medicine caused these liver problems because some patients had other illnesses or were taking other medicines.
• Some patients taking this medicine can develop serious problems with their pancreas (pancreatitis), which may cause death. You have a higher chance of having pancreatitis if you have had it before. Tell your doctor if you have nausea, vomiting, or abdominal pain. These may be signs of pancreatitis.
• Some patients have large increases in triglycerides and cholesterol. The long-term chance of getting complications such as heart attacks or stroke due to increases in triglycerides and cholesterol caused by protease inhibitors is not known at this time.
• Diabetes and high blood sugar (hyperglycemia) occur in patients taking protease inhibitors such as this medicine. Some patients had diabetes before starting protease inhibitors, others did not. Some patients need changes in their diabetes medicine. Others needed new diabetes medicine.
• Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.
• Some patients with hemophilia have increased bleeding with protease inhibitors. There have been other side effects in patients taking this medicine. However, these side effects may have been due to other medicines that patients were taking or to the illness itself. Some of these side effects can be serious. If you suspect that you took more than the prescribed dose of this medicine, contact your local poison control center or emergency room immediately. As with all prescription medicines, this medicine should be kept out of the reach of young children.

What medications interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)?

Always inform your physician about the drugs you are taking till date. Provide complete list of prescription or non prescription drugs and any other disease. This way, your physician will assist you with the list of medicine and other things that may interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets).

Warnings & Precautions When Using Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

• Do not take this medicine if you have had a serious allergic reaction to Lopinavir or Ritonavir (the active ingredients).
• This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby.
• You should tell your doctor if you have liver problems or are infected with Hepatitis B or Hepatitis C.
• Some people taking protease inhibitors develop new or more serious diabetes or high blood sugar. Be sure to tell your doctor if you have diabetes or an increase in thirst and/or frequent urination. Some people with hemophilia have had increased bleeding. It is not known whether the protease inhibitors caused these problems. Be sure to tell your doctor if you have hemophilia types A and B. Together with your doctor, you need to decide whether this medicine is right for you.
• Do not take this medicine if you are taking certain other medicines. These could cause serious side effects that could cause death. Before you take this medicine, you must tell your doctor about all the medicines you are taking or are planning to take.

Zidovir (Zidovudine 100mg Capsule)

Zidovir (Zidovudine 100mg Capsule) contains Zidovudine as an active ingredient. Zidovudine belongs to a class of nucleoside reverse-transcriptase inhibitor (NRTI). It is a blood brain barrier permeable. Zidovudine is an antiretroviral medicine used to treat HIV infection. It is used along with other HIV medications to treat HIV.

What is Zidovir (Zidovudine 100mg Capsule) used for?

Zidovir (Zidovudine 100mg Capsule) is given to patients who suffer from HIV to treat and control their infection, and to reduce the risk of other HIV related illnesses. This drug is a type of nucleoside reverse transcriptase inhibitor, or NRTI, which works by slowing down the spread of HIV in the body. Apart from the above mentioned uses, this drug is also sometimes given to pregnant women with HIV to prevent it being passed to an unborn baby, or to prevent infection in somebody who has come into contact with the virus.

How to Zidovir (Zidovudine 100mg Capsule)  use

Take Zidovir (Zidovudine 100mg Capsule) by mouth 2 to 3 times a day with or with out food as directed by your doctor. Do not miss the dose as drug should be maintained at constant level for better treatment.

How does Zidovir (Zidovudine 100mg Capsule) work?

Zidovir (Zidovudine 100mg Capsule)Zidovir (Zidovudine 100mg Capsule) works by blocking an HIV enzyme called, HIV reverse transcriptase. By doing this, it prevents HIV from replicating and decreases the amount of HIV in the blood.

Working of the drug:

Zidovudine is a nucleoside reverse transcriptase inhibitors (ntris) drug that works by blocking the enzyme called reverse transcriptase. This enzyme is an essential part of replication mechanism of HIV and thus, the drug reduces the amount of infectious virus in the body.

How should Zidovir (Zidovudine 100mg Capsule) be taken?

• Zidovir (Zidovudine 100mg Capsule) comes in the form of a capsule. Taking Zidovir (Zidovudine 100mg Capsule), with a glass of water will help you to swallow it.
• To treat HIV infection in adults: The usual dose of Zidovir (Zidovudine 100mg Capsule) is 600 mg/ day, and it should be taken in divided doses. It is to be taken together with other antiretrovirals agents.
• To treat HIV in pediatrics who aged 4 -<18 years, the dosage regimen is based upon the body weight. Your doctor will prescribe this medicine according to the weight of your child. Alternatively, treatment with Zidovir (Zidovudine 100mg Capsule) may also be based on body surface area for every child. The usual dose is of Zidovudine is 480mg/m2 in divided doses (240 mg/m2 two times a day or 160 mg/m2 three times a day).
• For the prevention of mother-to-child  HIV-1 transmission:

Maternal Dosing- The usual dose of Zidovir (Zidovudine 100mg Capsule) is 100 mg five times a day, until the labor start. During labor and delivery, 2mg/kg of the medicine should be administered intravenously over one hour followed by 1 mg/kg/hour until clamping of the navel string.

Neonatal Dosing: The usual dose of Zidovir (Zidovudine 100mg Capsule) is 2 mg/kg every 6 hours starting within twelve hours after the birth of a child, and the treatment should be continued for 6 weeks of age. In neonates, Zidovir (Zidovudine 100mg Capsule) should be administered intravenously at 1.5 mg/kg, infused over 30 minutes every six hours.

• Do not take more or less amount of capsule than your doctor has prescribed.
• Do not stop taking the capsules without asking your doctor.
• Take the medicine continuously as long as your doctor recommends you. Zidovir (Zidovudine 100mg Capsule) is a drug that prevents further damage caused by the HIV, but it does not cure your condition. You should not stop taking the drug and continue taking it, even if you feel better. Because stopping the intake of the drug may reverse your improving condition.
• Overdose: If you accidently take an extra capsule, call your doctor or hospital casualty department immediately.

Zidovir (Zidovudine 100mg Capsule) Overdose:

If you feel any frightening symptoms, then immediately call the doctor and inform him about the possible side effects of over dosage. If the situation worsens then visit the nearest healthcare center or call the emergency helpline number.

Zidovir (Zidovudine 100mg Capsule) Miss dose:

In case you forget to take the dose, skip the dose and take the next dose on the recommended time period. Do not double up the dose for the missed one.

What are Side effects of Zidovir (Zidovudine 100mg Capsule)?

Like all drugs, Zidovir (Zidovudine 100mg Capsule) can cause side-effects although, not everyone gets them. Contact your doctor, if any of the following symptoms appear:

• Constipation
• Nausea
• Diarrhea
• Blurred vision
• Vomiting
• Constipation
• Headache

Some side effects of Zidovir (Zidovudine 100mg Capsule) can be serious. Call your doctor immediately, if you experience:

• Chills
• Numbness, tingling or burning sensation
• Liver problems
• Skin rashes
• Hives

The side effects that are mentioned above are not the only ones that you may experience due to Zidovir (Zidovudine 100mg Capsule). If you get any serious adverse effects due to Zidovir (Zidovudine 100mg Capsule), call your doctor right away.

What medications interact with Zidovir (Zidovudine 100mg Capsule)?

The following medicines should be avoided, in case doctor recommends you Zidovir (Zidovudine 100mg Capsule) to avoid possible drug interactions.

• Ganciclovir
• Rifampicin
• Doxorubicin
• Sulfa drugs
• Lamivudine
• Sulfa drugs

What is Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets)?

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) containing the 2 active ingredients tenofovir disoproxil fumarate and emtricitabine is considered a nucleoside reverse transcriptase inhibitors (NRTIs) type of medication. The medication works by controlling and preventing the HIV cells from multiplying in the body to help the immune system work better. It should be used in combination with other medications to lower the chance of suffering from HIV complications and slowing the progression of the disease from HIV to AIDS. Using more than 1 type of medication can prevent the body from becoming immune to the treatment.

What is Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) used for?

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over age 18. Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) are used combination with other medications that have a different mechanism of action to the components in Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets), and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4 cell numbers, so that the immune system can recover, reducing the risk of disease progression.

 How does Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) work?

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) contain a combination of two antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate, which are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Emtricitabine and tenofovir disoproxil fumarate are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Emtricitabine is an analogue of cytidine and tenofovir is an analogue of adenosine. The combined action of these two antiiretroviral drugs in Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) prevents the integration of the virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus). Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Tenvir-EM Adverse effects

Patients using Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) may encounter unwanted side effects such as:

• Nausea
• Vomiting
• Diarrhea
• Headaches
• Dizziness
• Strange dreams
• Stomach pain
• Insomnia

Contact a doctor immediately should side effects persist or encounter more severe side effects such as:

• Irregular heartbeat
• Tremors
• Joint pain
• Severe lower back pain
• Signs of new infections
• Unexplained weight loss
• Signs of overactive thyroid
• Mental or mood changes

Tenvir-EM Dosage and Administration

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) should be taken strictly in accordance with the prescription given to you by your physician or pharmacist. The dosage varies from case to case, but most often it is one tablet taken once a day with some water with or without food. Do not discontinue or change the dosage of the medication without checking with your doctor first.

 Precautions

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) can be harmful for patients suffering from existing medical conditions like hepatitis B, bone, liver or kidney disease. If you suffer from an existing medical condition, you will have to be monitored closely while you are on this treatment. Therefore it is advisable that your physician has your complete medical history prior to starting the medication. Your physician will also need to know if you are

• Allergic to any medication
• You are currently taking any medication, supplement and vitamins
• You are breastfeeding, pregnant or trying to conceive
• You are having any herbal supplements

Please inform your physician if you currently have any existing allergic conditions. It is also advisable to seek a doctor’s consultation if you feel that you may have an adverse reaction to the medication.

 Warnings

Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.

The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets)

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) are indicated for the treatment of hiv-1 infection in adults. It is recommended that Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) be taken on an empty stomach, preferably at bedtime. Bedtime dosing may improve the tolerability of nervous system symptoms associated with efavirenz. The increased efavirenz concentrations observed following administration of efavirenz with food may lead to an increase in the frequency of adverse events. Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) are not indicated for use in pediatric patients.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) is a combination of tenofovir, lamivudine, and efavirenz to treat hiv infected people. Each film-coated tablet contains 600 mg of efavirenz, 300 mg of lamivudine and another 300 mg of tenofovir disoproxil fumarate. It can be taken alone and with combination of other medications. This medication helps to control the hiv infection and help to improve the quality of life. In additions, it lowers the risk to get hiv complications like new infections, cancer. It does not cure the infection perfectly, but somehow prevent the spread to others through sexual contact or blood contamination, including sharing the needles.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) Uses

Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children and also used in the treatment of Hepatitis B virus infection.

How it Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) works

Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells). It does not cure HIV completely but reduces the chances of getting acquired immunodeficiency syndrome (AIDS) and HIV related infections or cancer.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) Contraindications:

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) is contraindicated in patients with hypersensitive to any of the components of the product. It should not be administered concurrently with astemizole, bepridil, cisapride, midazolam, pimozide, and triazolam or ergot derivatives. It is because for cyp3a4 as efavirenz could result in the inhibition of the metabolism of this medication and can create a serious life threatening adverse events, including cardiac arrhythmias, prolonged sedation, or respiratory depression. Again it should not be administered concurrently with voriconazole as it is significantly decreased voriconazole plasma concentrations.

This medication is dangerously contraindicated with amprenavir, fosamprenavir, calcium, atazanavir, indinavir, lopinavir, ritonavir, saquinavir, warfarin, carbamazepine, phenytoin, phenobarbital, setailine, itraconazole, ketoconazole, clarithromycin, rifampin, rifabutin, avorvastin, paravastin, simvastatin, methadone, ethinyl estradiol, ditiazem.

It is better to tell your doctor before medication and be frank if you take any other medication, including all the prescription and non-prescription medications, also if you take vitamins and other herbal products.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) Dosage and Administrations:

One tablet once a day is the recommended dosage of Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) medicine. It can be taken on an empty stomach for the best result most preferably at bedtime because during this time it may improve the tolerability of nervous system symptoms associated with efavirenz. Administration of this medicine with a high-fat meal increased the mean AUC and Cmax of efavirenz by 28% and 79% respectively, and in combination of Tenofovir and lamivudine with a high-fat meal or a light meal increased the mean AUC and Cmax of Tenofovir by 35% and 15% respectively and it does not affect Lamivudine exposures.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Introduction

Dinex EC (Didanosine Delayed - Release 400mg Capsules) is an oral antiretroviral agent which is active against HIV infection. This drug is a synthetic purine derivative and similar to stavudine and zidovudine which inhibits the reverse transcriptase enzyme. The drug blocks reproduction of the human immunodeficiency virus which affects people causing AIDS. It inhibits replication of HIV by preventing DNA replication. It is used in combination with other antiretroviral drugs in the treatment of HIV infection and AIDS.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Use

This drug is known to be used as treatment to HIV infection and postexposure prevention following occupational or nonoccupational exposure to HIV with other antiretrovirals.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Dosage and administration

The recommended total daily dose is based on body weight and administered as one capsule given once a day. The recommended total daily dose of pediatric patients with a weight of less than 20 kg and who can swallow is based on body weight. The initial dose is 250 mg while doctor may also increase the dose up to 400 mg. Doses may be taken in 1 to 2 divided doses. In infants, dose is 50 to 100 mg/m2 twice daily.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Important Precautions

Give drug on an empty stomach at least 30 minutes before or 2 hours after meals to avoid decreasing the absorption. IF pancreatitis is suspected, stop giving the drug and don't continue until pancreatitis is ruled out. Adequate hydration is required unless instructed to restrict fluid intake. Inform those with preexisting liver dysfunction that hepatoxicity may result due to therapy. Inform physician if you have a kidney disease, since you may need a lower dosage. Take drug at exact prescribed timing since missing doses may increase the chance of virus becoming resistant to HIV medications.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Side effects

The common side effects of the drug are nausea, vomiting, diarrhea or changes in body fat. Report immediately if there are instances of any loss of sensation, numbness, or tingling in fingers, toes or feet; persistent unresolved abdominal distress, changes in vision, or signs of infection such as burning on urination, perineal itching, and white plaques in mouth, unhealed sores, persistent sore throat and cough. Adverse reactions may also occur such as aggressive reaction, allergic reaction, convulsion, liver failure and neuropathy.

Other important Information on Dinex Ec Capsule

Missing a dose

In case you miss a dose, take it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not take extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Overdosage of Dinex EC (Didanosine Delayed - Release 400mg Capsules)

Do not take more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side effects. If you suspect that you or anyone else who may have overdosed of Dinex EC (Didanosine Delayed - Release 400mg Capsules), please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.

Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.

Storage of Dinex EC (Didanosine Delayed - Release 400mg Capsules)

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Dinex EC (Didanosine Delayed - Release 400mg Capsules).

Expired Dinex EC (Didanosine Delayed - Release 400mg Capsules)

Taking a single dose of expired Dinex EC (Didanosine Delayed - Release 400mg Capsules) is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to take expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.

What is Dinex EC (Didanosine Delayed - Release 250mg Capsules)?

Dinex EC (Didanosine Delayed - Release 250mg Capsules) is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body. Dinex EC (Didanosine Delayed - Release 250mg Capsules) is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Dinex EC (Didanosine Delayed - Release 250mg Capsules) is not a cure for HIV or AIDS. Dinex EC (Didanosine Delayed - Release 250mg Capsules) may also be used for purposes not listed in Dinex EC (Didanosine Delayed - Release 250mg Capsules) guide. Overdose symptoms may include some of the serious side effects listed in Dinex EC (Didanosine Delayed - Release 250mg Capsules) guide.

Pancreatitis

Fatal and non-fatal pancreatitis has occurred during therapy with did anosine used alone or in combination regimens in both treatment-naïve and treatment-experienced patients, regardless of degree of immunosuppression.  Dinex EC (Didanosine Delayed - Release 250mg Capsules)should be suspended in patients with signs or symptoms of pancreatitis. Patients treated with Dinex EC (Didanosine Delayed - Release 250mg Capsules) in combination with stavudine, with or without hydroxyurea, may be at increased risk for pancreatitits.

When treatment with life-sustaining drugs known to cause pancreatic toxicity is required, suspension of didanosine therapy is recommended. In patients with risk factors for pancreatitis, Dinex EC (Didanosine Delayed - Release 250mg Capsules) should be used with extreme caution and only if clearly indicated.  Patients with advanced hiv-1 infection, especially the elderly, are at increased risk of pancreatitis and should be followed closely. Patients with renal impairment may be at greater risk for pancreatitis if treated without dose adjustment.the frequency of pancreatitis is dose-related.

Lactic acidosis/Severe Hepatomegaly with Steatosis

Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including didanosine and other antiretrovirals. A majority of these have been in women. Obesity and prolonged nucleoside exposure may be risk factors. Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk (see warnings and precautions, pregnancy).particular caution should be exercised when administering didanosine to any patient with known risk factors for liver disease; however, cases have also been reported in patients with no known risk factors. Treatment with Dinex EC (Didanosine Delayed - Release 250mg Capsules) should be suspended in any patient who develops clinical signs or symptoms with or without laboratory findings consistent with symptomatic hyperlactatemia, lactic acidosis, or pronounced hepatoxicity (which may include hepatomegaly and steatosis even in the absence of marked transaminase elevations).

Hepatic Toxicity

The safety and efficacy of Dinex EC (Didanosine Delayed - Release 250mg Capsules) have not been established in hiv-infected patients with significant underlying liver disease. During combination antiretroviral therapy, patients with pre-existing liver dysfunction, including chronic active hepatitis, have an increased frequency of liver function abnormalities, including severe and potentially fatal hepatic adverse events, and should be monitored according to standard practice. If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.

Hepatotoxicity and hepatic failure resulting in death were reported during postmarketing surveillance in hiv-infected patients treated with hydroxyurea and other antiretroviral agents.  Fatal hepatic events were reported most often in patients treated with the combination of hydroxyurea, didanosine and stavudine. This combination should be avoided.

Non-cirrhotic Portal Hypertension

Postmarketing cases of non-cirrhotic portal hypertension have been reported, including cases leading to liver transplantation or death. Cases of didanosine-associated non-cirrhotic portal hypertension were confirmed by liver biopsy in patients with no evidence of viral hepatitis.  Onset of signs and symptoms ranged from months to years after start of didanosine therapy. Common presenting features included elevated liver enzymes, esophageal varices, hematemesis, ascites, and splenomegaly.

Patients receiving Dinex EC (Didanosine Delayed - Release 250mg Capsules) should be monitored for early signs of portal hypertension (eg, thrombocytopenia and splenomegaly) during routine medical visits. Appropriate laboratory testing including liver enzymes, serum bilirubin, albumin, complete blood count, and international normalized ratio (inr) and ultrasonography should be considered. Dinex EC (Didanosine Delayed - Release 250mg Capsules)(Didanosine Delayed - Release 250mg Capsules)should be discontinued in patients with evidence of non-cirrhotic portal hypertension.

Immune Reconstitution Syndrome

Immune reconstitution syndrome has been reported in patients treated with combination antiretroviral therapy, including Dinex EC (Didanosine Delayed - Release 250mg Capsules). During the initial phase of combination antiretroviral treatment, patients whose immune system responds may develop an inflammatory response to indolent or residual opportunistic infections (such as mycobacterium avium infection, cytomegalovirus, pneumocystis jirovecii pneumonia , or tuberculosis), which may necessitate further evaluation and treatment.

Autoimmune disorders (such as graves’ disease, polymyositis, and guillain-barré syndrome) have also been reported to occur in the setting of immune reconstitution; however, the time to onset is more variable, and can occur many months after initiation of treatment.

Pregnancy

Pregnancy Category B:

Reproduction studies have been performed in rats and rabbits at doses up to 12 and 14.2 times the estimated human exposure (based upon plasma levels), respectively, and have revealed no evidence of impaired fertility or harm to the fetus due to didanosine. At approximately 12 times the estimated human exposure, didanosine was slightly toxic to female rats and their pups during mid- and late-lactation. These rats showed reduced food intake and body weight gains but the physical and functional development of the offspring was not impaired and there were no major changes in the f2 generation. A study in rats showed that didanosine and/or its metabolites are transferred to the fetus through the placenta. Animal reproduction studies are not always predictive of human response.

There are no adequate and well-controlled studies of didanosine in pregnant women. Didanosine should be used during pregnancy only if the potential benefit justifies the potential risk.

Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. It is unclear if pregnancy augments the risk of lactic acidosis/hepatic steatosis syndrome reported in non-pregnant individuals receiving nucleoside analogs (see warnings and precautions). The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk. Healthcare providers caring for hiv-infected pregnant women receiving didanosine should be alert for an early diagnosis of lactic acidosis/hepatic steatosis syndrome.

Pediatric Use

Use of didanosine in pediatric patients from 2 weeks of age through adolescence is supported by evidence from adequate and well-controlled studies of didanosine in adult and pediatric patients (seedosage and administration; undesirable effects; pharmacology). Additional pharmacokinetic studies in pediatric patients support the use of didanosinein pediatric patients who weigh at least 20 kg.

Geriatric Use

In an expanded access program using a buffered formulation of didanosine for the treatment of advanced hiv infection, patients aged 65 years and older had a higher frequency of pancreatitis (10%) than younger patients (5%) (see warnings and precautions). Clinical studies of didanosine, including those for Dinex EC (Didanosine Delayed - Release 250mg Capsules), did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently than younger subjects. Didanosine is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection. In addition, renal function should be monitored and dosage adjustments should be made accordingly (see dosage and administration).

Overdosage

There is no known antidote for didanosine overdosage.  In phase 1 studies, in which buffered formulations of didanosine were initially administered at doses ten times the currently recommended dose, toxicities included:pancreatitis, peripheral neuropathy, diarrhea, hyperuricemia, and hepatic dysfunction. Didanosine is not dialyzable by peritoneal dialysis, although there is some clearance by hemodialysis

Dinex EC (Didanosine Delayed - Release 250mg Capsules) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Dinex EC (Didanosine Delayed - Release 250mg Capsules) may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

• Muscle pain or weakness.
• Numb or cold feeling in your arms and legs.
• Trouble breathing; feeling dizzy, light-headed, tired, or very weak.
• Stomach pain, nausea with vomiting.
• Fast or uneven heart rate.

Stop using Dinex EC (Didanosine Delayed - Release 250mg Capsules) and call your doctor at once if you have any of these other serious side effects:

• Signs of a new infection such as flu symptoms, easy bruising or unusual bleeding, loss of appetite, mouth sores.
• Severe pain in your upper stomach spreading to your back, nausea and vomiting; itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• Swelling around your stomach, feeling of fullness, feeling short of breath, coughing up blood;
• Numbness, tingling, or pain in your hands or feet.
• Pain in one or both eyes, vision problems, seeing flashes of light.
• Pale skin, easy bruising or bleeding, feeling light-headed, rapid heart rate, trouble concentrating.
• Increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia).
• Diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex.
• Swelling in your neck or throat (enlarged thyroid).
• weakness or prickly feeling in your fingers or toes.
• Problems with walking, breathing, speech, swallowing, or eye movement.
• severe lower back pain, loss of bladder or bowel control.

 Less serious side effects  may include:

• Mild skin rash;
• Diarrhea; headache;
• Changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

What is Efavir (Efavirenz 600mg Tablets)?

Efavir (Efavirenz 600mg Tablets) containing the active ingredient efavirenz belongs to a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). The medication works by decreasing the amount of HIV in the body and preventing the cells from multiplying to allow the immune system to work better. It must be used along with other medications to decrease the chance of developing acquired immunodeficiency syndrome (AIDS) and HIV related illnesses such as serious infections or cancer.

How does Efavir (Efavirenz 600mg Tablets) work?

Efavir (Efavirenz 600mg Tablets) (also known as Sustiva) contain efavirenz, a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), which is only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Efavirenz in Efavir (Efavirenz 600mg Tablets) acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA. This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus). Efavir (Efavirenz 600mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

When should Efavir (Efavirenz 600mg Tablets) not be used?

You should not use Efavir (Efavirenz 600mg Tablets) if you:

• are allergic to efavirenz or any ingredients in Efavir (Efavirenz 600mg Tablets)
• are pregnant or are breastfeeding
• have liver disease
• are using Efavir (Efavirenz 600mg Tablets) as a single treatment as it is intended for use only as part of combination therapy
• are taking medicines that interact with Efavir (Efavirenz 600mg Tablets), including: other antiretrovirals, such as, amprenavir, indinavir, atazanavir, ritonavir, saquinavir, the antibiotics rifampicin, rifabutin and clarithromycin, the antifungals voriconazole and itraconazole, cholesterol lowering statins like simvastatin and atorvastatin, the antiepileptic carbamazepine, oestrogen containing oral contraceptives, methadone for opioid dependence, the dietary supplement St. John's Wort, the antidepressant sertraline, calcium channel blockers like diltiazem for angina and hypertension, the antihistamine terfenadine, cisapride for reflux, triazolam for anxiety, the sedative midazolam, ergot derivatives for migraine, the antipsychotic pimozide, bepridil for angina

How should Efavir (Efavirenz 600mg Tablets) be taken?

You should take your Efavir (Efavirenz 600mg Tablets) swallowed whole with a glass of water without food, once a day preferably on an empty stomach at bedtime to reduce problems with side effects.  The dose you take depends on your body weight and your doctor’s recommendation.   You should continue to take your Efavir (Efavirenz 600mg Tablets) regularly for as long as your doctor recommends, and you condition should be monitored. Do not suddenly stop taking your Efavir (Efavirenz 600mg Tablets) as this may increase risk of HIV resistance.

Missed dose of Efavir (Efavirenz 600mg Tablets)

If you miss a dose of Efavir (Efavirenz 600mg Tablets) take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

Efavir (Efavirenz 600mg Tablets) Side effects

Be aware of the possible side effects that Efavir (Efavirenz 600mg Tablets) can cause. Certain reactions are listed here:

• Nausea
• Fatigue
• Vertigo
• Lipodystrophy
• Concentration difficulties

Your physician will regularly conduct various medical assessments so that your condition can be monitored. All side effects (no matter how mild) must be thoroughly reported. Rarely, serious reactions will occur. Should you experience bloody urine, abnormal behavioral disturbances, significant appetite reduction, speech problems, unexplained weigh increases or any other severe side effects, see your physician immediately.

Efavir (Efavirenz 600mg Tablets) Warnings

1. The medication can be used to treat HIV but cannot be used to cure HIV or decrease the risk of transmitting the HIV virus to other people.
2. Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.
3. Efavir (Efavirenz 600mg Tablets) is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.
4. The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.

Stavir (Stavudine 30mg Capsules)

Stavir (Stavudine 30mg Capsules) contains Stavudine as an active medicinal substance. Stavudine is a synthetic nucleoside, analog of deoxythymidine with potent antiretroviral activity. It is used along with other antiretroviral agents to treat human immunodeficiency syndrome or HIV-1 infection. Stavudine is an FDA-approved drug prescribed for the treatment of HIV-1 in infants, children, and adults.

Why is this medication prescribed?

Stavir (Stavudine 30mg Capsules) is used along with other medications to treat human immunodeficiency virus (HIV) infection. Stavir (Stavudine 30mg Capsules) is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although Stavir (Stavudine 30mg Capsules) does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other life-style changes may decrease the risk of transmitting (spreading) the HIV virus to other people.

What is Stavir (Stavudine 30mg Capsules) used for?

Stavir (Stavudine 30mg Capsules) is used to treat Human immunodeficiency syndrome or HIV-1 infection.  HIV is a lentivirus (a subgroup of retrovirus) that causes Acquired Immunodeficiency Syndrome (AIDS).  AIDS is a disease in which progressive failure of the immune system leads to opportunistic infections and cancers to prosper.

How does  Stavir (Stavudine 30mg Capsules)  work?

Stavir (Stavudine 30mg Capsules) works by blocking reverse transcriptase enzyme, preventing HIV-1 infection from multiplying in the body and can reduce the amount of HIV in the body of an infected person.

Missed dose of Stavir (Stavudine 30mg Capsules):

If you have forgotten a dose, take it as soon you remember and go back to your usual dosing schedule. If the time to take the next dose is near, leave the forgotten dose and take the next dose. Do not double up the dose to compensate the missed one.

• Take the capsule for as long as your doctor recommended.

What are Side effects of Stavir (Stavudine 30mg Capsules)?

Like other medicines, Stavir (Stavudine 30mg Capsules) may cause adverse effects. Seek medical attention, in case the following troubles arise:

• Neuropathy
• Vomiting
• Headache
• Diarrhea
• Nausea

Some adverse effects of Stavir (Stavudine 30mg Capsules) can be serious. Visit the doctor immediately, in the following situations.

• Rash
• Difficulty moving your hands and feet
• Burning, tingling, numbness in the hands or feet
• Pain in the hands and feet

When should Stavir (Stavudine 30mg Capsules) not be used?

Tell the doctor before consuming Stavir (Stavudine 30mg Capsules):

• If you are hypersensitive to the medicine, or its components.
• If you are taking alcohol products.
• If you have gallstones.
• If you have ever had problems with your pancreas and kidney diseases.
• If you have or ever had neuropathy.
• The drug may cause dizziness. Do not drive or use machinery, while taking Stavir (Stavudine 30mg Capsules) as these activities may require a high degree of mental attention.
• If you are pregnant or intending to become pregnant. You should discuss the benefits and risks of taking Stavir (Stavudine 30mg Capsules) during pregnancy. Breastfeeding women are advised not to take Stavir (Stavudine 30mg Capsules) as it may pass into breast milk and harm the nursing baby.

Remember the following things, to avoid transmission of HIV infection on to others:

• Avoid sharing needles and other injection equipment with other people.
• Avoid sharing personal things that can have blood fluid on them, like toothbrushes and razors.
• Avoid practicing sex without protection. Do practice safe sex by using polyurethane or latex to decrease the chance of sexual contact with vaginal secretions, semen, and blood.

How should Stavir (Stavudine 30mg Capsules) be taken?

• Stavir (Stavudine 30mg Capsules) comes in the form of a capsule. Swallow the capsule with a glass of water. It may be taken with or without a meal.
• The dosage of the drug is based on the body weight of a patient.
• To treat adults who weigh less than 60 kg: The recommended dose is 30 mg every 12 hours.
• To treat adult patients who weigh at least 60 kg: The recommended dose is 40 mg every 12 hours.
• To treat pediatric patients:

Infants from birth to 13 days old- The recommended dose are 0.5 mg/kg every 12 hours.

An infant who is at least 14 days old and whose weight is less than 30 kg- The recommended dose is 1 mg/kg every 12 hours.

• A paediatric patient whose weight is at least 30 kg: The recommended dosage is adult dosage.
• Take the capsule exactly as prescribed by the doctor. Do not alter the dosage plan.
• Overdose: Seek medical attention immediately, in the case of an overdose of Stavir (Stavudine 30mg Capsules).

Stavir (Stavudine 40mg Capsules)

Stavir (Stavudine 40mg Capsules) is used in combination with other anti-virus medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Stavir (Stavudine 40mg Capsules) will not cure or prevent HIV infection or AIDS. It helps to keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease.Stavir (Stavudine 40mg Capsules) will not keep you or your child from spreading HIV to other people. People who receive this medicine may continue to have the problems usually related to AIDS or HIV disease.

How it works Stavir (Stavudine 40mg Capsules)?

Stavir (Stavudine 40mg Capsules) acts by interfering with the viral reproductive system. It gets incorporated into viral DNA with the help of two enzymes, i.e. HIV reverse transcriptase and HBV polymerase and ultimately stops the formation of DNA. This way, it stops the DNA formation which is very vital for virus survival.  This way, it delays the progression of viral infestation in the  body.

How much to take Stavir (Stavudine 40mg Capsules)?

The dosage is solely decided by the Doctor after assessing your condition and various factors such as age, gender and body weight. One can’t fix the dose as it varies from patient to patient. The usual recommended dose is 30 mg once a day for 12 hours. It can be increased or decreased depending upon the patient’s condition. Always take the dose as prescribed by the Doctor.

When should you avoid it?

You should not take Stavir (Stavudine 40mg Capsules) if you:

• Are allergic to Stavir (Stavudine 40mg Capsules)
• Are prone to allergies
• Are suffering from kidney disease
• are suffering from pancreas problem
• Are suffering from diabetes
• Are overweight
• are pregnant or planning to conceive
• are breast feeding a child

What are the strengths available?

Stavir (Stavudine 40mg Capsules) is available in following strength preparation on our website:

• Stavir 40 mg
• Stavir 30 mg

What are the Stavir (Stavudine 40mg Capsules) side effects?

Every medicine shows some side effects, same way this drug also has some undesired effects with it. Stavudine shows common side effects such as:

• Headache
• Diarrhea
• Nausea
• Vomiting
• Loss of appetite
• Blurred vision
• Constipation

Some serious and rare side effects that need serious consideration are stated below:

• Skin rashes
• Hives
• Chills
• Liver problems
• Numbness, tingling or burning sensation

What if you miss the dose?

Try to take the medicine at the same time each day. This reduces the chances of missing a dose. Talk to your Doctor if you miss the dose. Don’t double up the dose in order to catch up with the previous one.

Are there any possible drug interactions?

Always inform your doctor about the drugs you are taking till date. Give a complete list of prescription or non prescription drugs and any other disease conditions. This way, the doctor is able to decide and give you the list of drugs and other things that may interact with Stavir (Stavudine 40mg Capsules). Few drugs like Didanosine, Zidovudine and hydroxyurea that may interact with Stavir (Stavudine 40mg Capsules).

What are the things to be taken care of?

• Always take the medicine as per the prescription
• Don’t use the expired drugs
• Don’t share your medicine with anybody, even if they have the same symptoms
• Avoid drinking alcohol while you take Stavir (Stavudine 40mg Capsules). Drinking alcohol may increase your risk of liver or pancreas problems.
• Stavir (Stavudine 40mg Capsules) may affect your blood sugar levels, check blood sugar levels closely
• Always store the medicine at the room temperature and away from moisture, heat and light
• This drug can cause severe dizziness so immediate consult with your doctor
• During pregnancy, one can take this medicine only after Doctor’s recommendation in order to prevent the further transmission of the HIV virus to the baby
• Consult with your pharmacist about the proper disposal of the drug
• Keep a complete record of all the medicines you are taking along with this medicine

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets)

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) is used in combination with other antiviral medications in patients with acquired immunodeficiency syndrome (AIDS). Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) is also used for the treatment of chronic hepatitis B infection.

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) belong to a class of antiretroviral drugs which are known as NRTI. NRTI stands for Nucleotide Analogue Reverse Transcriptase Inhibitors, which are essential in blocking a very crucial viral enzyme in HIV called, Reverse Transcriptase. This enzyme is also found in Hepatitis B virus. Thus, this drug becomes extremely essential as it is used in the treatment of two very life-threatening diseases, namely- AIDS and Hepatitis B. Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) is used for the treatment of chronic Hepatitis B in adults over and above 12 years of age, and along with a cocktail of antiretroviral agents, for the treatment of HIV-1 infection in patients 2 years of age and above. Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) are very effective weapons to combat these lethal scourges. Though, this drug should be used only after doctor’s prescription as it has considerable side-effects. Buy Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) online from Scorpion Healthcare and ease your pain.

How to Use Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets)

Take Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) exactly as your healthcare provider tells you to. Take it at the same time every day by mouth, with or without food. The usual dose of this medicine is 1 tablet each day.

Do not miss a dose of this medicine. If you miss a dose of Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets), take the missed dose as soon as you remember. If it is almost time for your next dose of this medicine, do not take the missed dose. Take the next dose of this medicine at your regular time.

If you are an adult and have kidney problems, your healthcare provider may tell you to take this medicine less often. If you take too much this medicine, call your local poison control center or go right away to the nearest hospital emergency room.

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) Side effects

The most common Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) side effects with an incidence greater than or equal to 10% are rash, diarrhea, headache, pain, depression, asthenia, and nausea.

Lactic acidosis (build-up of an acid in your blood) can happen in some people who take this medicine or similar medicines (nucleoside analog).  Lactic acidosis is a serious medical emergency that can lead to death. It can be hard to identify early, because the symptoms could seem like symptoms of other health problems. Call your healthcare provider right away if you get the following symptoms which could be signs of lactic acidosis:

• feeling very weak or tired
• have unusual (not normal) muscle pain
• have trouble breathing
• have stomach pain with nausea (feel sick to your stomach), vomiting
• feel cold, especially in your arms and legs
• feel dizzy or lightheaded
• have a fast or irregular heartbeat

Severe liver problems can happen in people who take this medicine or similar medicines. In some cases these liver problems can lead to death. Your liver may become large (hepatomegaly) and you may develop fat in your liver (steatosis) when you take this medicine. Call your healthcare provider right away if you have any of the following symptoms of liver problems:

• your skin or the white part of your eyes turns yellow (jaundice)
• dark "tea-colored" urine
• light-colored bowl movements (stools)
• loss of appetite for several days or longer
• nausea
• stomach pain

You may be more likely to get lactic acidosis or severe liver problems if you are female, very overweight (obese), or have been taking this medicine or a similar medicine for a long time. Hepatitis B Virus (HBV) infection may become worse (flare-up) if you take this medicine and then stop it. A "flare-up" is when your HBV infection suddenly returns in a worse way than before.

Do not let your medicine supply run out. Get a refill or talk to your healthcare provider before the medicine is all gone. Do not stop taking this medicine without first talking to your healthcare provider. If you stop taking this medicine, your healthcare provider will need to check your health often and do regular blood tests to check your HBV infection.

Tell your healthcare provider about any new or unusual symptoms you may have after you stop taking this medicine. Talk to your doctor about taking an HIV test before starting treatment with this medicine for chronic hepatitis B. You should also get a test for HBV if you are taking this medicine for treatment of HIV.

New or worse kidney problems can happen in some people who take this medicine. If you have had kidney problems in the past or need to take another medicine that can cause kidney problems, your healthcare provider may need to do blood tests to check your kidneys during your treatment with this medicine.

Bone problems can happen in some people who take this medicine. Bone problems include bone pain, softening or thinning (which may lead to fractures).Your healthcare provider may need to do additional tests to check your bones.

Changes in body fat can happen in some people who take antiviral medicines. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the main part of your body (trunk). Loss of fat from the legs, arms, and face may also happen. The cause and long-term health effects of these conditions are not known.

Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Tell your doctor if you start having new symptoms after starting your HIV medicine.

Tell your healthcare provider if you have any Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) side effect that bothers you or that does not go away. These are not all the possible side effects of this medicine. For more information, ask your healthcare provider.

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) Nursing Considerations

HIV-infected mothers should not breast-feed their infants to avoid risking postnatal transmission of HIV. Tenofovir is secreted in human milk.

Due to the fact that the potential for HIV transmission exists as well as the potential for serious adverse reactions in nursing infants, mothers should be instructed not to breast-feed if they are taking Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets).

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) During Pregnancy

Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets)has been classified by the US FDA as Pregnancy category B . There are no adequate and well-controlled studies in pregnant women.

Because animal reproduction studies are not always predictive of human response, Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets) should be used during pregnancy only if clearly needed. Do not use this medicine without your doctor's consent in case you are pregnant.

Warnings & Precautions When Using Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets)

Before you take Tenvir (Tenofovir Disoproxil Fumarate 300mg Tablets), tell your healthcare providers if you:

• have liver problems, including hepatitis B (HBV) infection
• have kidney problems
• have bone problems
• have any other medical conditions, including HIV infection

This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Tell your healthcare provider about all the medicines you take such as vitamins and herbal supplements. This medicine may interact with other medicines. Do not take this medicine if you take:

• other medicines that contain tenofovir (Truvada, Atripla)
• adefovir (Hepsera)

Especially tell your healthcare provider if you take the following medications, as the dose of these other medications may need to be changed:

• didanosine (Videx, Videx EC)
• atazanavir (Reyataz)
• lopinavir with ritonavir (Kaletra)

Know the medicines you take. Keep a list of them to show your healthcare provider when you get a new medicine.

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) is a combination of lamivudine and zidovudine, which belong to the nucleoside analog class of antiretroviral drugs. Each tablet of Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contains half of the commonly prescribed daily doses of both lamivudine and zidovudine. With the availability of this combination tablet, patients may be better able to adhere to complex drug treatment regimens, thereby enhancing compliance.

What is Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) used for?

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) are prescribed to treat HIV infection in patients with or without acquired immunodeficiency syndrome (AIDS). HIV directly affects the immune system by impairing the specific immune cells (CD4) that counter infection, so the risk of life-threatening infection increases. Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) medicine can prevent or slow down the ability of HIV to replicate, lowering the capacity of the virus. This medication functions to increase the number of CD4 cells, providing good strength to the immune system and defying the risk of disease.

How does Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) work?

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contain a combination of two antiretroviral drugs lamivudine and zidovudine, which both belong to class of drugs known as nucleoside analogue reverse transcriptase inhibitors (NRTI) that are only effective against retroviruses (RNA virus) like HIV. A nucleoside is a building block of DNA that is needed by the virus to replicate, and nucleoside analogues, like lamivudine and zidovudine in Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets), become incorporated into the DNA that is copied from the virus RNA by an enzyme called reverse transcriptase. This blocks the action of reverse transcriptase and terminates the viral DNA chain so that it cannot become integrated into the DNA of the infected immune cell, which means that no more HIV can be produced. Lamivudine is highly synergistic with zidovudine, which means that it increases the effectiveness of zidovudine so that the combination of these two antiretroviral drugs in Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) slow down the replication of HIV within your body but cannot prevent the spread of the infection to others.

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) Dosage and Administration

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contain 150mg of lamivudine and 300mg of zidovudine. The other variety available, Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) also contains 150mg of lamivudine and 300mg of zidovudine, as well as 200mg of nevirapine. Your physician will decide the required daily dosage and provide you with the necessary details related to the frequency of administration. It is essential that you fully comply with all directions given by your physician. Do not take more than the correct daily dosage, as this could put you at risk of serious health problems.

What does Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contain?

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) medicine has a combination of the active ingredients lamivudine (150mg) and zidovudine (300mg). Both of these are antiretroviral drugs that are used to treat HIV infection.

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) Side effects

Patients undergoing antiretroviral treatment with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) (Lamivudine/Zidovudine) should be aware that side effects are possible. These may include:

• Headaches
• A blocked nose
• Body fat movement
• Discomfort in the sinuses
• Insomnia or possible fatigue

The above mentioned side effects are usually considered mild, and patients should note that other reactions may also occur. Serious adverse events are generally less common. However, you must get to the hospital or consult a physician immediately if you notice aching of the muscles which does not go away, sores on the skin, soreness in the back that is severe, difficulty walking properly, tremors and any other severe side effects that have not been referenced here.

What medications interact with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)?

There is a list of medications that interact with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) so, they should be avoided along with this drug. Some particular drugs that may react with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) are anti-infective, pentamidine, amphotericin, flucytosine, vincristine, pyrimethamine, co-trimoxazole, the antiviral ganciclovir, dapsone, vinblastine and doxorubicin for cancer treatment. Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) should not be taken with some other agents like stavudine, emtricitabine, efavirenz, fosamprenavir, indinavir, ketoconazole, itraconazole, and probenecid.

 Some other drugs that are affected by Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) include stavudine, the anticonvulsant phenytoin, and antiretroviral zalicitabine.

When Duovir Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) not be taken?

• One should avoid Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) in the conditions of:
• Allergic to lamivudine or zidovudine or any ingredients in Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)
• Pregnancy or breastfeeding
• Abnormally low neutrophil counts
• Blood disorders such as anemia or bone marrow problems
• Kidney or liver disease
• Anxiety and sleeping problems
• Immune modulator interferon

How should Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) be taken?

 Usually, you should take Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) as 1 tablet twice daily with a glass of water and with or without food. Your doctor can determine how much and how long this medicine should be taken. If you miss a dose of Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) then take it as soon as you remember, but don’t increase the amount to make up the missed dose.

Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) Precautions

Treatment of HIV with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) cannot cure the virus. It will only help your body deal with and fight the infection. Therefore, it is essential that patients are aware of the risk posed to others who they may be in contact with. Take every necessary precaution to ensure that you do not infect anybody else with HIV.

Certain cases in which patients developed a severe and potentially life threatening disorder known as lactic acidosis have been reported. Ask your physician about the symptoms of this condition and get immediate medical help if you believe that you are affected by this condition.

Atavir (Atazanavir 300mg Capsules)

Atavir (Atazanavir 300mg Capsules) selectively inhibits the virus-specific processing of viral Gag and Gag-Pol polyproteins in HIV-1 infected cells by binding to the active site of HIV-1 protease, thus preventing the formation of mature virions. Atavir (Atazanavir 300mg Capsules) is not active against HIV-2.

Atavir (Atazanavir 300mg Capsules) Use

Atavir (Atazanavir 300mg Capsules) Atazanavir Sulphate is a prescription medicine used in combination with other medicines to treat people who are infected with the human immunodeficiency virus (HIV). Atavir (Atazanavir 300mg Capsules) has been studied in 48 week trials in both patients who have taken or have never taken anti HIV medicines.

How it Atavir (Atazanavir 300mg Capsules) works

Atavir (Atazanavir 300mg Capsules) belongs to a group of medication called azapeptide HIV-1 protease inhibitor. It inhibits some viral polypeptides in the HIV-1 infected cells of the body and inhibits and prevents maturation of virus in the cells. Atavir (Atazanavir 300mg Capsules) does not cure HIV infections; it decreases the risks of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses due to compromised immunity.

Atavir (Atazanavir 300mg Capsules) side effects

and redistribution/accumulation of body fat., cardiac conduction abnormalities, asymptomatic hyperbilirubinemia, nephrolithiasis, fatigue, nausea, Headache, abdominal pain, dyspepsia, vomiting, new onset or exacerbations of diabetes mellitus, insomnia, depression, cholelethiasis, diarrhea, dizziness, fever, ocular icterus, immune reconstitution syndrome, rash, lipodystrophy syndrome, myalgia, liver toxicity, jaundice

Atavir (Atazanavir 300mg Capsules) Precautions & How to Use

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

• Avoid spreading of HIV virus to others
• Kidney problems
• Liver problems or liver disease including hepatitis B or C

Other important Information on Atavir (Atazanavir 300mg Capsules)

Missing a dose

In case you miss a dose, take it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not take extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Overdosage of Atavir (Atazanavir 300mg Capsules)

Do not take more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side effects. If you suspect that you or anyone else who may have overdosed of Atavir (Atazanavir 300mg Capsules), please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.

Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.

Please consult your physician or pharmacist or product package for more information.

Storage of Atavir (Atazanavir 300mg Capsules)

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Atavir (Atazanavir 300mg Capsules).

Expired Atavir (Atazanavir 300mg Capsules)

Taking a single dose of expired Atavir (Atazanavir 300mg Capsules) is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to take expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.

What is Adesera (Adefovir Dipivoxil 10mg Tablets)?

Adesera (Adefovir Dipivoxil 10mg Tablets) is an antiviral medicine. It is used to treat long-term hepatitis B virus infection of the liver. Adesera (Adefovir Dipivoxil 10mg Tablets) decreases the amount of virus in your body and therefore reduces further liver damage. However, it may not prevent hepatitis B complications such as liver cancer or end stage liver damage. It also does not prevent the spread of hepatitis B to other people.

Adesera (Adefovir Dipivoxil 10mg Tablets) is an antiviral medication. It works by preventing viral cells from multiplying in the body and infecting new liver cells. Adesera (Adefovir Dipivoxil 10mg Tablets)  is used to treat chronic hepatitis B in adults. This medicine will not cure hepatitis. Adesera (Adefovir Dipivoxil 10mg Tablets)  may also be used for purposes not listed in this medication guide. This medication is used to treat a chronic viral infection of the liver ( hepatitis B ) in people 12 years of age and older. It works by slowing the growth of the virus. It is not a cure for hepatitis B and does not prevent the passing of hepatitis B to others.

Uses Adesera (Adefovir Dipivoxil 10mg Tablets)?

Adesera (Adefovir Dipivoxil 10mg Tablets) is used for treating symptoms of chronic inflammation of the liver (hepatitis) caused by hepatitis B virus (chronic hepatitis B).

Common side effects Adesera (Adefovir Dipivoxil 10mg Tablets)

Weakness, cough, nausea, running nose., vomiting, rash or itching on skin, tiredness, diarrhea, gas, headache

How it works Adesera (Adefovir Dipivoxil 10mg Tablets)?

Adefovir is a nucleotide analogue. It works by slowing the growth of the hepatitis B virus.

What is Abamune (Abacavir Sulfate 300mg Tablets)?

Abamune (Abacavir Sulfate 300mg Tablets) will not prevent your body of HIV. You can still prone this syndrome among other people through infected blood (via needles, razors, toothbrush) or through unsafe sexual arousal (ensure safe barrier contraception). Make sure to remember all these things and employ safe measure to prevent infection. You must not take Abamune (Abacavir Sulfate 300mg Tablets) drug with any other medicine that also comprised of Abamune (Abacavir Sulfate 300mg Tablets) content. Lactic acidosis has been observed in some people (especially overweight women and those have liver disease) who are taking Abamune (Abacavir Sulfate 300mg Tablets). The initial stage symptoms of lactic acidosis may deteriorate over the time and can prove fatal. You must seek medical care immediately when you encounter the first sign of lactic acidosis such as muscle pain or weakness, breathing trouble, numb or cold feeling in the limbs, stomach pain, or nausea with vomiting. It can also cause severe damage to your liver. Get medical attention quickly if you have any of the following conditions of liver damage: severe pain in upper stomach which advances to the back, nausea and vomiting, fast heartbeats, itching, loss of appetite, dark urine, clay colored stools, or jaundice.       

It belongs to FDA pregnancy category C drug. It is not known whether this drug can harm an unborn baby if taken during the pregnancy time. However, HIV can be passed into the baby if mother is not treated safely during pregnancy. Always remember to take medicines for HIV as advised by your doctor to prevent your baby from this dreadful syndrome.

How it works Abamune (Abacavir Sulfate 300mg Tablets)?

Abamune (Abacavir Sulfate 300mg Tablets)  belongs to a group of medicines called nucleoside analogue reverse transcriptase inhibitors (NRTIs). Abamune (Abacavir Sulfate 300mg Tablets)  works by blocking the function of reverse transcriptase, which inhibits replication of HIV thereby decreasing its level in the blood.

Side Effects Abamune (Abacavir Sulfate 300mg Tablets)

Some common side effects pertaining to this medicine are trouble sleeping, or loss of appetite. If these effects persist or deteriorate, seek medical attention or contact your doctor immediately. Increase in fat deposition may occur while taking Abamune (Abacavir Sulfate 300mg Tablets). Some patients may feel deterioration of previous medical condition as they experience the recovery, or develop new condition due to overactive immune system. Inform your doctor if you have any of these conditions. It may also increase the risk of bone loss.

Working of the drug Abamune (Abacavir Sulfate 300mg Tablets):

Abamune (Abacavir Sulfate 300mg Tablets) inhibits reverse transcriptase of HIV and prevents the proper transcription of the viral DNA. It inhibits the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The chain elongation process is inhibited and finally the viral DNA growth is inhibited

Warning Abamune (Abacavir Sulfate 300mg Tablets):

Things to remember:

• Do not get up quickly or suddenly from a sitting or lying position as doing so may make you feel dizzy and you might fall as well. Instead get up slowly
• Abamune (Abacavir Sulfate 300mg Tablets) may impact your thinking capabilities and reflexes. So, take extra care while indulging in activities that require a high degree of mental awareness and thinking such as driving
• Avoid alcohol as it can increase the likelihood of side effects of Abamune (Abacavir Sulfate 300mg Tablets)
• Do not share your medicine with anyone else

What is Lamivir (Lamivudine 150mg Tablet)?

Lamivir (Lamivudine 150mg Tablet) containing the active ingredient lamivudine is considered a nucleoside reverse transcriptase inhibitor (NRTI) type of medication. The medication can help decrease the amount of the HIV cells from multiplying in the body to allow the immune system to work better. The tablets should be taken with other medication to lower the chance of getting HIV complications such as AIDS, serious infections or cancer. It can be used to help treat HIV but cannot be used to cure the condition.

Lamivir (Lamivudine 150mg Tablet) Uses

Lamivir (Lamivudine 150mg Tablet) is indicated for use in conjunction with other antiretroviral medicines to treat HIV-1 infections. It works by stopping the virus from spreading and destroying CD4 helper cells. This medicine is classified as a nucleoside analog and its mechanism of action involves blocking the action of the viral RT (reverse transcriptase, an enzyme that the virus needs to replicate), and this results in the termination of the viral DNA chain. The HIV virus can develop a resistance to drugs, and a particular type of mutation of which occurs in the reverse transcriptase gene (called the M184V mutation) may occur if this medicine is used on its own. Resistance can reduce the effectiveness of the medicine, and to combat this, your physician will also advice concomitant treatment with other medicines to ensure that the infection is kept under control.

How does Lamivir (Lamivudine 150mg Tablet) work?

Lamivir (Lamivudine 150mg Tablet) contain lamivudine, which is a nucleoside analogue reverse transcriptase inhibitor (NRTI) that is only effective against retroviruses (RNA virus) like HIV. Lamivudine in Lamivir (Lamivudine 150mg Tablet) 150mg works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. A nucleoside is a building block of DNA that is needed by the virus to replicate, and nucleoside analogues, like lamivudine (analogue of cytidine) in Lamivir (Lamivudine 150mg Tablet), become incorporated into the DNA that is copied from the viral RNA by an enzyme called reverse transcriptase. This blocks the action of reverse transcriptase and terminates the viral DNA chain so that it cannot become integrated into the DNA of the infected immune cell, which means that no more HIV can be produced. Lamivudine in Lamivir (Lamivudine 150mg Tablet) has been shown to act additively or synergistically with other anti-HIV agents particularly zidovudine, which means that that it increases the effectiveness of the other drug. Lamivir (Lamivudine 150mg Tablet) helps slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Lamivir (Lamivudine 150mg Tablet) Dosage and Administration

Lamivir (Lamivudine 150mg Tablet) are provided as a 150mg strength formula, and dosage is by means of oral administration. Patients may take it without regard to meals, however those who find it difficult to swallow the tablet should contact their physician for advice. It is essential that no doses are missed, as doing so could increase the likelihood of developing viral resistance. Your physician will calculate the right dosage for you. In most cases, adults treating an infection caused by HIV will be told to administer 150mg (one tablet) twice per day, and your physician will also decide for you (based on your unique circumstances) what other antiretroviral medicines you need to take. Strict compliance with the physician`s instructions is required at all times.

Lamivir (Lamivudine 150mg Tablet) Side effects

Patients who take Lamivir (Lamivudine 150mg Tablet) might suffer from side effects, such as:

• Insomnia
• Dyspepsia
• Blocked nose
• Concentration problems
• Cramps which affect the abdomen

It is vital that a physician is kept informed of all side effects which occur throughout the course of treatment. The occurrence of serious and harmful reactions is generally considered to be less common, however all patients are advised to be aware of this risk. Visit your physician or attend the emergency room straight away should you suffer from fever, discolored urine, weakness or any other severe side effects that have not been referenced here.

Lamivir (Lamivudine 150mg Tablet) Warnings

Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.

Lamivir (Lamivudine 150mg Tablet) is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.

The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.

When should Lamivir (Lamivudine 150mg Tablet) not be used?

You should not use Lamivir (Lamivudine 150mg Tablet) if you:

• are allergic to lamivudine or any ingredients in Lamivir (Lamivudine 150mg Tablet)
• are taking any other retroviral medication containing lamivudine
• are pregnant or are breastfeeding
• have kidney or liver disease
• are taking medicines that interact with Lamivir (Lamivudine 150mg Tablet), including: the antibiotic trimethoprim, the antriretrovirals zalicitabine

How should Lamivir (Lamivudine 150mg Tablet) be taken?

You should take your Lamivir (Lamivudine 150mg Tablet) with a glass of water, with or without food, once or twice daily. The dose you take depends on your condition and your doctor’s recommendations and should be taken in combination with other HIV medication. You should continue to take your Lamivir (Lamivudine 150mg Tablet) 150mg for as long as recommended by your doctor, and you will be monitored carefully to ensure that you do not develop any serious side effects, in which case your doctor will probably recommend that you stop taking your Lamivir (Lamivudine 150mg Tablet). Do not suddenly stop taking your Lamivir (Lamivudine 150mg Tablet) as this may increase risk of HIV resistance.

Lamivir (Lamivudine 150mg Tablet) Precautions

Lamivir (Lamivudine 150mg Tablet) cannot cure HIV. Therefore, patients are still able to infect others. Precautions such as practicing safe sex can ensure that the risk of infecting others is minimized.

Serious risks associated with this medicine include liver disease (which has the potential to be fatal) and lactic acidosis. Ensure that you discuss the risks of this with your physician prior to commencing treatment.

Viraday Tablets(Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets)

Viraday Tablets (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) contains  different anti-retroviral drugs that are effective in treatment of retroviruses (RNA viruses) such as Human Immunodeficiency Virus (HIV).

Viraday Tablets (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets)Uses

Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) is a combination medicine used to treat HIV (Human Immunodeficiency Virus) in adults. Each tablet contains a combination of three antiretroviral drugs: Tenofovir Disoproxil Fumarate (Viread) 300mg + Emtricitabine (Emtriva) 200mg + Efavirenz (Sustiva) 600mg.

Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) contains three different anti-retroviral drugs that are effective in treatment of retroviruses (RNA viruses) such as Human Immunodeficiency Virus (HIV). Replication of the HIV virus is caused by the action of viral-specific enzyme reverse transcriptase. These drugs inhibit the action of these enzymes.

How  Viraday Tablets (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) work?

Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) contain a combination of three antiretroviral drugs, efavirenz, emtricitabine and tenofovir disoproxil fumarate, which are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These three drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides, which are the precursors to the building blocks of DNA and RNA. Tenofovir and Emtricitabine are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Emtricitabine is an analogue of cytidine and tenofovir is an analogue of adenosine. The combined action of the three antiiretroviral drugs in Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) prevents the integration of the virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus). Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

What do I do if I miss a Viraday Tablets dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

Viraday Tablets (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) Side effects

Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) can result in some unwanted side effects, especially at the beginning of treatment. Many side effects will be minor and temporary. The most common side effects of Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) are:

• Headaches
• Gastrointestinal conditions (nausea, diarrhea, constipation, stomach pain)
• Loss of appetite or eating disorders
• Dizziness and/or fatigue
• Rashes, hot flushes or other skin conditions
• Mood changes, depression, anxiety
• Nightmares, trouble sleeping, insomnia

A very rare, but potentially fatal adverse effect of Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) is lactic acidosis, a build up of lactic acid in the blood due to liver damage, liver enlargement or fatty deposits in the liver. This can lead to liver failure, kidney failure or pancreatits, and even fatality if left untreated.

When should Viraday Tablets (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) not be used?

You should not use Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) tablets if you:

• are allergic to efavirenz, emtricitabine and tenofovir or any ingredients in Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets)
• are pregnant or are breastfeeding
• have kidney or liver disease
• have hepatitis B infection
• have a mental illness, including depression; convulsions; or bone disease like osteoporosis without discussion with your doctor, as your condition may worsen
• are taking medicines that interact with Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets), including: cisapride for reflux, midazolam and triazolam for sedation and anxiety, the antipsychotic pimozide, bepridil for angina, Cafergot for migraine, the antifungal voriconazole and Itraconazole, other medications containingf efavirenz, emtricitabine, or tenofovir, other retrovirals like ritonavir or lamivudine, herbal preparations containing St. John's wort, the anticonvulsant phenobarbital, antibiotics like clarithromycin rifampicin, statins like simvastatin for lowering cholesterol, the anticoagulant warfarin, the anticonvulsants carbamazepine and Phenytoin, the antidepressant sertraline, the calcium channel blocker diltiazem for high blood pressure, oral contraceptives

Viraday Tablets (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) Precautions

Viraday (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg, Efavirenz 600mg Tablets) is not suitable for everybody. You should discuss with your doctor any of the following:

• if  allergic to tenofovir, emtricitabine or efavirenz
• if you have had reactions to any other medicines
• if you are pregnant, trying to become pregnant, or breastfeeding
• if you suffer from kidney or liver disease
• if you have any infections, especially hepatitis B
• if you have any form of mental illness including depression
• if you have any bone disease including osteoporosis
• if you are taking any other medicines including prescription drugs, non-prescription drugs, nutritional supplements or herbal treatments

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets)

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) contains three drugs: Lamivudine, Nevirapine and Zidovudine. It is the medicine that is used with other HIV drugs for the control of HIV infections. This drug is very effective in decreasing the chances of a person getting infected with this virus. It improves the condition of the patient.

Lamivudine and Zidovudine are both NRTIs i.e. Nucleoside reverse transcriptase inhibitors while Nevirapine is a non-NTRIs(NNTRIs).

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) is a combination of three drugs commonly used in the management of the human immunodeficiency virus (hiv) infection. Both zidovudine and lamivudine belong to the nucleoside analogue class of antiretroviral drugs. Both drugs act by terminating the growth of the dna chain and inhibiting the reverse transcriptase (rt) of hiv. Nevirapine is a non-nucleoside reverse transcriptase inhibitor (nnrti). It acts by directly inhibiting rt. Each tablet of Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) contains half of the commonly prescribed daily doses of zidovudine, lamivudine and nevirapine. Usually, all three drugs are to be administered twice daily, permitting a fixed-dose combination to be formulated. With the availability of this combination formulation, patients may be better able to adhere to triple drug regimens, thereby enhancing compliance.

Uses of the drug:

This medicine is used for HIV infections. HIV is Human Immunodeficiency Virus; this virus is responsible for spreading AIDS disease. HIV can be transmitted through blood transfusion, mother to child during pregnancy and through sexual contact with infected persons etc.

How does Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) work?

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) contain a combination of three antiretroviral drugs; nevirapine, zidovudine and lamivudine, which are effective only against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These three drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Nevirapine in Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) is a non-nucleoside reverse transcriptase inhibitor (NNRTI); nucleosides are the precursors to the building blocks of DNA and RNA. Nevirapine in Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) acts by binding to a specific site on the RT enzyme, the enzyme's active site known as the NNRTI pocket, disrupting the catalytic site of the enzyme, and blocking its action in a manner that is noncompetitive with nucleosides. Zidovudine and lamivudine are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Zidovudine is an analogue of thymidine and lamivudine is an analogue of cytidine. The combined action of the three antiiretroviral drugs in Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) prevents the integration of the virus into the DNA of the infected CD4+ immune cell by 2 different mechanisms, which inhibits the replication of HIV so that no more virus can be produced, and this reduces the viral load (amount of virus). Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) slows down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Dosage Adjustment

Because Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) is a fixed-dose combination, they should not be prescribed for patients requiring dosage adjustment such as those with reduced renal function (creatinine clearance <50 ml/min), or hepatic impairment, or those experiencing dose-limiting adverse events.

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) should be discontinued if patients experience severe rash or a rash accompanied by constitutional findings (see warnings and precautions). Patients experiencing mild to moderate rash during the 14-day lead-in period of 200 mg/day should not have their nevirapine dose increased or start therapy with Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) tuntil the rash has resolved (see warnings and precautions). If rash persists beyond the 14-day lead-in period, do not dose escalate to Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) twice daily. The Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) once-daily dosing regimen should not be continued beyond 28 days, after which an alternative regimen should be sought.

If a clinical (symptomatic) hepatic event occurs, nevirapine should be permanently discontinued and not be restarted after recovery .

Patients who interrupt nevirapine dosing for more than 7 days should restart the recommended dosing, using one 200 mg nevirapine tablet daily for the first 14 days (lead-in) in combination with the lamivudine + zidovudine, followed by Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) twice daily in the absence of any signs of hypersensitivity.

Before you take this drug:

Do not take this drug if you:

• Are allergic to this drug or any of the other ingredients of this medicine
• Are pregnant, take all the medicine for HIV prescribed by the doctor, to prevent the spread of HIV to the unborn baby.
• Are breastfeeding or planning to breast feed
• Have very low WBC/ RBC count

Tell your doctor if you:

• Have kidney problems
• Have liver abnormalities
• Have problem related to pancreas
• Have nervous system abnormalities
• Have muscle related problems

Dosage:

How much to take the drug?

Lamivudine dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly.

The recommended dose in children/adults having a body weight above 25 kg or more is one tablet twice in a day. Children weighing below 25 kg are not recommended to take the drug.

How to take the drug?

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) comes as capsule and is taken orally with water. Take this medication with a full glass of water. Follow the directions given by the doctor on your prescription carefully and take is exactly as directed by the doctor. Do not take more or less than the prescription.

Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) can be taken with or without food. Discuss the time of the day the drug should be taken with your doctor and take the capsule as prescribed by him. Take the dose at the correct time and that too the correct quantity because the improvement of the condition of the patient depends upon the correct dose taken at correct time.

For how long to take it?

Continue to take the drug for as long as the doctor recommends. Do not stop taking the medicines without consulting the doctor. Stopping the dose or taking it more often than recommended may cause an increase in the amount of viruses and will make this situation worse and difficult to treat.

Overdose:

Too much Duovir-N (Lamivudine 150mg, Zidovudine 300 mg and Nevirapine 200mg Tablets) or in fact of any other drug is ought to cause some or the other kind of changes in the body. These changes sometimes might be severe and harmful. So, one should never exceed the dose without recommendation from the doctor. In such a case, visit nearest healthcare center or call the emergency helpline number.

Side effects of the drug:

Tell your doctor as soon as possible if you notice any of the following:

• Nausea
• Diarrhea
• Stuffy nose
• Muscle pain
• Unexplained weight loss
• Joint pain
• Vision changes
• Skin rashes, hives and itching
• Tiredness
• Heat intolerance
• Thyroid gland enlargement or goiter
• Increased bruising or bleeding
• Signs of pancreatitis

In above situations you must go for immediate medical help. Do not get alarmed by the list. You may /may not experience all of them. Tell your doctor immediately in the above situations. Discuss with him about the risks and benefits of this treatment.

Common drug interactions:

There are certain drugs that might interfere in the action of the other drugs. Some interactions may result in serious side effects. The following drugs interact with this drug:

• Interferon Alfa
• Probenecid
• Ribavirin
• Stavudine
• Zalcitabine

Some medicines are involved in the removal of Zidovudine such as Fluconazole, Rifampin, and Valproic Acid.

Tell your doctor about all the drugs you have taken in past or are taking including the herbal drugs. Ask your doctor to get the full list of the drugs needed to be avoided while taking the drug as they may interfere it and may cause adverse effects.

Warning:

Things to remember:

• This drug will not keep you from spreading HIV to others so, take the necessary precautions
• The serious effects of this drug mostly occur in women and obese people
• Tell the doctor immediately if the liver problems worsens
• Keep regular contact with your doctor in case of emergency
• Patients should never miss the dose as it’s a part of combination therapy

Indivan (Indinavir Sulphate 400mg Capsules)

Indivan (Indinavir Sulphate 400mg Capsules) is used in the treatment of human immunodeficiency virus ( HIV) infection. Indivan (Indinavir Sulphate 400mg Capsules) is an inhibitor of the human immunodeficiency virus ( HIV) protease. Each capsule of Indivan (Indinavir Sulphate 400mg Capsules) contains Indinavir sulphate equivalent to Indinavir 400 mg. Active Pharmaceutical IngredientThe active pharmaceutical ingredient contained in Indivan (Indivan (Indinavir Sulphate 400mg Capsules) Sulphate 400mg Capsules) is Indinavir Sulfate. Uses Of Indivan Indivan (Indinavir Sulphate 400mg Capsules)is used to treat HIV infection in some patients, when used in combination with certain other medicines called antiretroviral agents. Indivan (Indinavir Sulphate 400mg Capsules) is an HIV protease inhibitor. It works by slowing the growth of HIV, the virus that causes AIDS. Indivan (Indinavir Sulphate 400mg Capsules) – DosageUse Indivan (Indinavir Sulphate 400mg Capsules) as directed by your doctor. Check the label on the medicine for exact dosing instructions. The recommended dosage of indinavir is 800 mg ( usually two 400-mg capsules) orally every 8 hours.

Indivan (Indinavir Sulphate 400mg Capsules) Uses

Indivan (Indinavir Sulphate 400mg Capsules) is used to treat HIV (human immunodeficiency virus) infection along with other medications.

Indivan (Indinavir Sulphate 400mg Capsules) works

Indivan (Indinavir Sulphate 400mg Capsules) belongs to a class of medications called retroviral protease inhibitors. It works by blocking the activity of an enzyme protease which results in formation of defective viruses and decreases the viral load in body. Indivan (Indinavir Sulphate 400mg Capsules) also lowers the risk of getting illness related to HIV and improves immunity.

Indivan (Indinavir Sulphate 400mg Capsules) Dosage

Use Indivan (Indinavir Sulphate 400mg Capsules) as directed by your doctor. Check the label on the medicine for exact dosing instructions. The recommended dosage of indinavir is 800 mg (usually two 400-mg capsules) orally every 8 hours.

• An extra patient leaflet is available with Indivan (Indinavir Sulphate 400mg Capsules). Talk to your pharmacist if you have questions about this information.
• For optimal absorption, Indivan (Indinavir Sulphate 400mg Capsules) should be administered without food but with water 1 hour before or 2 hours after after eating. You may also take it with a light meal that is low in calories, fat, and protein e.g., dry toast with jelly, juice, and coffee with skim milk and sugar. Take Indivan (Indinavir Sulphate 400mg Capsules) with water. You may also take it with other liquids such as skim milk, juice, coffee, or tea.
• Drinking extra fluids while you are taking Indivan (Indinavir Sulphate 400mg Capsules) is recommended. You should drink at least 48 ounces (1.5 L) of water a day unless otherwise directed by your doctor.
• If you take didanosine, ask your doctor or pharmacist how to take it with Indivan (Indinavir Sulphate 400mg Capsules).
• Large amounts of garlic may decrease the effectiveness of Indivan (Indinavir Sulphate 400mg Capsules). Talk with your doctor before including garlic in your diet.
• Eating grapefruit or drinking grapefruit juice while you are taking Indivan (Indinavir Sulphate 400mg Capsules) may increase the amount of Indivan (Indinavir Sulphate 400mg Capsules) in your blood, which may increase your risk for serious side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
• Take Indivan (Indinavir Sulphate 400mg Capsules) on a regular schedule every 8 hours around the clock, unless otherwise directed by your doctor.
• Take Indivan (Indinavir Sulphate 400mg Capsules) regularly to receive the most benefit from it. Taking Indivan (Indinavir Sulphate 400mg Capsules) at the same time each day will help you remember to take it.
• Continue to take Indivan (Indinavir Sulphate 400mg Capsules) even if you feel well. Do not miss any doses.
• If you miss a dose of Indivan (Indinavir Sulphate 400mg Capsules) by more than 2 hours, do not take that dose. Take your next dose as scheduled. If you miss the dose by less than 2 hours, take that dose immediately and then return to your regular dosing schedule. It is important not to miss doses of Indivan (Indinavir Sulphate 400mg Capsules). Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Indivan (Indinavir Sulphate 400mg Capsules) .

Can I take Indivan (Indinavir Sulphate 400mg Capsules) with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Back pain, blood in the urine, or fever or chills. Very upset stomach or throwing up. Very loose stools (diarrhea). More trips to the bathroom, more thirst, or weight loss. Any rash. Side effect or health problem is not better or you are feeling worse.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

Side Effects of Indivan (Indinavir Sulphate 400mg Capsules)

Below are listed the possible side effects of Indivan (Indinavir Sulphate 400mg Capsules). It should be noted that many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

• Bad taste in the mouth, diarrhea, dizziness, drowsiness, headache, nausea, tiredness, vomiting, weakness.
• Seek medical attention right away if any of these severe side effects occur.
• Severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue).
• Back, flank, or side pain.
• Bloody or cloudy urine.
• Change in the amount of urine, changes in appetite.
• Chest pain; chills; confusion, dark urine.
• Fast or irregular heartbeat.
• Fever, flushed face, heartburn, ingrown toenails.
• Joint or muscle aches, mental or mood changes.
• Numbness of the mouth, one-sided numbness or weakness.
• Pain while urinating, pale stools.
• Red, swollen, or blistered skin.
• Severe dizziness or fainting.
• Severe or persistent stomach pain or upset.
• Speech problems.
• Swelling of the feet, hands, lower legs, or stomach.
• Unusual hair loss, unusual paleness, unusual tiredness, unusually dry skin, vision changes, weight changes, yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.

Warnings and Precautions to be taken when using Indivan (Indinavir Sulphate 400mg Capsules)

Do NOT use Indivan (Indinavir Sulphate 400mg Capsules) if:

• you are allergic to any ingredient in Indivan (Indinavir Sulphate 400mg Capsules)
• you are taking alfuzosin, amiodarone, astemizole, atazanavir, certain benzodiazepines (eg, alprazolam, midazolam, triazolam), certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), cisapride, an ergot derivative (eg, ergonovine, ergotamine), erythromycin, pimozide, a proton pump inhibitor (eg, omeprazole), rifampin, a serotonin 5-HT1 receptor antagonist (eg, eletriptan, sumatriptan), St. John's wort, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Indivan (Indinavir Sulphate 400mg Capsules) Important safety information:

• Indivan (Indinavir Sulphate 400mg Capsules) may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Indivan (Indinavir Sulphate 400mg Capsules) with caution. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to it.
• Indivan (Indinavir Sulphate 400mg Capsules) is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
• Indivan (Indinavir Sulphate 400mg Capsules) does not stop the spread of HIV to others through blood or sexual contact. Use barrier forms of contraception (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
• When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Indivan (Indinavir Sulphate 400mg Capsules) , even for a short period of time. If you do, the virus may grow resistent to the medicine and become harder to treat.
• Indivan (Indinavir Sulphate 400mg Capsules) may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice signs or symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Indivan (Indinavir Sulphate 400mg Capsules)
• Changes in body fat may occur while you are taking Indivan (Indinavir Sulphate 400mg Capsules) (eg, increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss any new questions or concerns with your doctor.
• Indivan (Indinavir Sulphate 400mg Capsules) may raise your blood sugar. High blood sugar can make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor immediately.
• Diabetes patients - Indivan (Indinavir Sulphate 400mg Capsules) may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Hormonal birth control (eg, birth control capsules) may not work as well while you are using Indivan (Indinavir Sulphate 400mg Capsules) . To prevent pregnancy, use an extra form of birth control (eg, condoms).
• Lab tests, including liver function tests, cholesterol tests, blood counts, and CD4 counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Caution is advised when using Indivan (Indinavir Sulphate 400mg Capsules) in children; they may be more sensitive to its effects, especially kidney stones.
• Pregnancy and breast-feeding: if you become pregnant, contact your doctor. Mothers infected with hiv should not breast-feed. There is a risk of passing the hiv infection or Indivan (Indinavir Sulphate 400mg Capsules) to the baby. It is not known if Indivan (Indinavir Sulphate 400mg Capsules) is found in breast milk. Do not breast-feed while taking Indivan (Indinavir Sulphate 400mg Capsules).