Cipla

What is Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) are used to slow down the progression of HIV infection which can lead to AIDS and other related illnesses. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) do not cure AIDS or destroy the HIV virus, but rather delay any further damage to the immune system by stopping production of new viruses.

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) is taken with other antiretroviral medications to treat adults infected with HIV-1. A single pill is the equivalent of 300mg of lamivudine IP and 600mg of abacavir. At least one other anti-HIV medication must be co-administered with Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) to effectively prevent HIV from progressing to AIDS.

Used For Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) is a combination of two medications, abacavir and lamivudine which belong to a class of medicines called antiretrovirals. They are used together with other antiretrovirals to slow down the progression of HIV infection (human immunodeficiency virus), which can lead to AIDS (Acquired Immune Deficiency Syndrome) and other related illnesses for example, AIDS – related Complex or ARC.

Dosing & Administration Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)

The recommended dose of Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) for adults is one pill daily along with other antiretroviral medications. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) may be taken with or without food.

Drug Interactions Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)

Ethanol may hinder the kidneys' ability to eliminate abacavir. Zalcitabine cannot be coadministered with Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) because zalcitabine and lamivudine inhibit one another.

Work Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

The two medications abacavir and lamivudine combined together help prevent HIV from reproducing. The HIV virus is responsible for acquired immune deficiency syndrome as HIV infection destroys CD4 (T) cells, which are important to the body’s immune system. The immune system is what helps fight infections. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) do not cure AIDS or destroy the HIV virus, but rather delay further damage to the immune system by stopping production of new viruses. Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) do not reduce the risk of passing infection to others. It is important that you continue to take precautions to prevent this from happening as the HIV virus can still be passed on by sexual activity or by contamination with infected blood.

Overdose Warning Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)

The effects of an Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) overdose are at this point unknown. Do not take more than the recommended dose

Side effects of Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets)?

Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) can cause some side effects. If they do occur and some may be serious, seek medical advice from your health professional as you may require medical attention. As Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) contain both abacavir and lamivudine, the side effects reported for each of these have been combined. It has been reported that the most common side effects which could affect at least one to ten in every 100 people include nausea, vomiting, diarrhoea, upper abdominal pain, headache, high temperature, lethargy, fatigue, loss of appetite, hair loss, joint and muscle pain, abacavir hypersensitivity and skin rash. Less common side effects which could affect less than 1 in every 100 people include increased liver enzyme production, anaemia (low red blood cell count), neutropenia (low white blood cell count), reduced number of blood cells important for blood clotting.

You may show symptoms of tiredness or breathlessness if the production of red blood cells is reduced. A reduction in your white blood cell count can make you more susceptible to infection.

Rare side effects which could affect less than one in every 1000 people are breakdown of muscle tissue, increases of an enzyme called amylase and inflammation of the pancreas. Very rare side effects which could affect less than one in every 10,000 people are serious skin reactions and severe anaemia. It has been documented that any changes in fat distribution are associated with antiretroviral medications, which may include loss of fat from legs, arms and face and also increased fat in the abdomen and other internal organs, breasts and the back of the neck. Changes in the amount of fatty substances and glucose in the blood have also been reported. Within the first few weeks of commencing treatment with anti-HIV medicines, some people and in particular those that have been HIV positive for some time, may develop inflammatory reactions for example, pain, redness, swelling and high temperature which may resemble an infection and may be severe. If you notice any changes in your health after commencing HIV treatment or become concerned with any new symptoms, then it is advisable you discuss this with your medical professional immediately. If you experience any of the following, call your doctor immediately. Lactic Acidosis – if you become very sick with accelerated breathing, you may have a condition known as this. High acid levels in the blood can cause rapid breathing and be life threatening. This is more common in women than men. If you experience allergic reactions soon after starting Abamune-L (Abacavir, Lamivudine  600mg 300mg Tablets) medication, for example wheezing, any swelling of the lips/mouth, difficulty in breathing, hay fever, hives or fainting then call your doctor immediately. Like all medications, there may be other side effects that occur in some people that are not listed or some side effects that are not yet known.

Efavir (Efavirenz 200mg Tablets)

The main active ingredient is Efavir (Efavirenz 200mg Tablets), Non-nucleoside Reverse Transcriptase Inhibitors, used actively against HIV or AIDS virus. This medicine is quite effective to reduce the discomfort and severity of AIDS and it is a very popular part of antiretroviral therapy.

Efavir (Efavirenz 200mg Tablets) used for?

Efavir (Efavirenz 200mg Tablets) (also known as Sustiva) are used with other HIV medications as part of combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection in adults and children three years of age or older.  Efavir (Efavirenz 200mg Tablets) must not be used alone as the virus can develop resistance if used as monotherapy and Efavir (Efavirenz 200mg Tablets) is, therefore, combined with two other drugs that have a different mechanism of action.  This treatment regime is known as highly active antiretroviral therapy (HAART) and is designed to minimise the ability of the virus to multiply and help prevent development of viral resistance to treatment.  HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful).  Also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS).  Efavir (Efavirenz 200mg Tablets) slows down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level (reduces viral load) and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression. 

Efavir (Efavirenz 200mg Tablets) work?

Efavir (Efavirenz 200mg Tablets) (also known as Sustiva) contain efavirenz, a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), which is only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV).  It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate.  Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate.  Efavirenz in Efavir (Efavirenz 200mg Tablets) acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA.  This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus).  Efavir (Efavirenz 200mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others. 

Dosage form and strengths:

This drug is available in the tablet form in the following strength on our website:

1. Efavirenz tablets 200 mg
2. Efavirenz tablets 600 mg

Efavir (Efavirenz 200mg Tablets) Dosage:

How much to take the drug?

The dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly. The usual dose is one 200/600 mg tablet once in a day, although the dose strength will depend upon the condition of the patient.

How to take the drug?

Swallow the tablet with one glass full of water. Do not break the tablet. Take the drug exactly as directed. Take the medicine on empty stomach, or as directed by your doctor. HIV is usually treated with a combination of drugs. Always take the prescribed drugs as directed by your doctor in combination with other HIV drugs. The drug comes with a warning card that lists the symptoms of allergic reactions. Read this card and carry if always with you. Take the tablet at the same time each day, so as to avoid forgetting the dose. This should become a habit for you to take the tablet until the doctor tells you to stop the drug.

For how long to take it?

This drug controls the multiplication of HIV but does not cure the problem. Take the drugs as long as your doctor recommends you to take it. .

Overdose:

If you feel any alarming symptoms then immediately consult the doctor about this drug and its possible side effects of over dosage. If the situation worsens then visit the nearest healthcare center or call the emergency helpline number.

Miss dose:

In case you forget to take the dose, skip the dose and take the next dose on the recommended time period. Do not double up the dose for the missed one.

Efavir (Efavirenz 200mg Tablets) Side effects:

Efavir (Efavirenz 200mg Tablets) can lead to severe psychiatric problems such as severe depression, confusion, suicidal thoughts, aggression, extreme fear, hallucinations, or unusual behavior. Inform you doctor right away if you get any of these side effects while taking Efavir (Efavirenz 200mg Tablets), even if you have had them before. Also, tell your doctor as soon as possible if you notice any of the following:

• Diarrhea
• Fat gain or loss
• Muscle pain
• Unexplained weight loss
• Seizures
• Headache
• Joint pain
• Vision changes
• Skin rashes, hives and itching
• Tiredness

In such cases you must go for immediate medical help. Do not get alarmed by the list. You may /may not experience all of them. Tell your doctor immediately in the above situations.

Efavir (Efavirenz 200mg Tablets) Warning:

Things to remember:

1. You must use a proper barrier contraceptive method while taking Efavir (Efavirenz 200mg Tablets) and for at least 12 weeks following the end of you treatment
2. Discuss them with your doctor and clear all doubts which you may have about this drug
3. Store this medication in a cool and dry place
4. Never start a new medication without consulting your doctor first

Usage of Tugain 5 (Minoxidil Topical Solution 60ml):

Apply Tugain 5 (Minoxidil Topical Solution 60ml) two times a day during morning and evening on scalp and hair is dried up and clean only in the area of hair loss. Rub at the center where it is exaggerated and extend the solution tenderly to cover up the whole part. Ensure the solution dries for 4 hours prior to cleaning or before sleeping. Soak the hands with soap without delay. Take utmost care to rub Tugain 5 (Minoxidil Topical Solution 60ml) only to the healthy scalp and where the skin is is unbroken and avoid unnecessary growth of hair on the other areas of the body.

Growth of new hair will be visible in three to four months with constant use of Regaine. Irregularity will lead to loss of new hair. Shouldn’t apply more than two times per day and cover for the missed schedule. Apply Tugain 5 (Minoxidil Topical Solution 60ml) when you remember should there be any missing dose.

It must be stored in a dry and cool place at 25 degree Centigrade secluded from light.

Tugain 5 (Minoxidil Topical Solution 60ml) is used externally and as prescribed only. Maximum quantity to be applied is not more than 2 ml. Frequency is two times per day. It must be used for 45 days minimum to seize the fall of hair. Do not take orally or apply on any other parts of the body and keep away from unnecessary growth of hair.

Tugain 5 (Minoxidil Topical Solution 60ml) is applied tenderly and not rubbed down on the scalp. Do not usage of hairdresser and avoid reduction in the efficiency. Do not club it with hair oil of any kind.

Tugain 5 (Minoxidil Topical Solution 60ml)  work?

Tugain 5 (Minoxidil Topical Solution 60ml) contains minoxidil, which is a vasodilator (dilates or widens blood vessels) and is thought to directly stimulate hair follicles to grow by increasing blood flow in the scalp and enhancing cell proliferation in hair follicles that were in resting phase. Another possible mechanism is that minoxidil in Tugain 5 (Minoxidil Topical Solution 60ml) prolongs the active growth phase of hair (anagen) and increases the size of the hair follicle, which prevents hair growth entering the resting phase (telogen) too early. Hair loss is due to shrinking hair follicles that gradually produce smaller and thinner hairs, which eventually do not emerge from the follicle. The longer hair follicles are inactive the harder it is for them to respond and begin new growth.

Tugain 5 (Minoxidil Topical Solution 60ml) Adverse effects:

Local irritation (that includes redness) at the place where Tugain 5 (Minoxidil Topical Solution 60ml) is applied frequently transpires unpleasant effect. This also includes rash, dried up skin, burning sensation, itching and flaking of scalp. Increase in the hair loss induces tainted color of hair or quality initially as the aged hair are replaced by brand new ones and its contact on the forehead may lead to unnecessary growth of hair.

Treating hair loss with Tugain 5 (Minoxidil Topical Solution 60ml):

Tugain 5 (Minoxidil Topical Solution 60ml) is the contemporary cure for baldness in male human beings. Hair loss becomes stable and provokes re-growth of hair by using Tugain 5 (Minoxidil Topical Solution 60ml). This is applied in places only where the hair is thinned out and not in the front or diminishing hair pattern. It is highly successful in areas where of latest hair loss. Baldness can’t be treated by Tugain 5 (Minoxidil Topical Solution 60ml) and only avoid sequence of hair loss the front and vertex. Women can’t use this for female version of baldness.

Tugain 5 (Minoxidil Topical Solution 60ml) that is a Vasodilator (expends or enlarges blood vessels) present in Tugain 5 (Minoxidil Topical Solution 60ml) is of notion to have straight arousal of hair follicles to increase the flow of blood in the scalp and augment cell production in follicles that are inactive. Also it delays the dynamic hair growth and enhances the size of hair follicle that anchors the growth of hair being inactive.

Decreasing hair follicles cause hair loss which steadily generate thin hair and not surface ultimately from the follicle. Longer the motionlessness of hair follicles tougher will be the response and hair re-growth.

Tugain 5 (Minoxidil Topical Solution 60ml) Side Effects?

Tugain 5 (Minoxidil Topical Solution 60ml) is very effective and potent lotion used to treat male pattern baldness but like every medicine, it also possesses some side effects. This is not necessary that each individual will encounter them.

Some common side effects are listed below:

• Itching
• Redness and flaking of the skin
• Headache and irritation
• Allergic reactions like breathing problems
• Dizziness and lightheadedness
• Swollen lips, face and tongue
• Irregular heartbeat
• Convulsions
• Fainting

Are there any possible drug interactions?

Always tell your doctor about the medicines you are taking. These medicines might interact with Tugain 5 (Minoxidil Topical Solution 60ml) and cause serious allergic reactions. Doctors will provide you a list of the drugs that will interact with Tugain 5 (Minoxidil Topical Solution 60ml) and can bring changes in its therapeutic efficacy. Avoid the application of the other topical solution while using the Tugain 5 (Minoxidil Topical Solution 60ml).

What are the things to be taken care of?

• Always apply the lotion in the correct amount as prescribed by the doctor
• Don’t use the expired topical lotion
• keep it away from fire as this lotion is flammable
• Pregnant women should avoid coming in contact with the drug
• Seek medical help if you experience any unusual conditions
• Apply the drug regularly to get the desired effect

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop)

It constitutes a generic name Norfloxacin., which belongs to class of fluoroquinolone antibiotic that fights against bacteria. This active ingredient is used to treat bacterial infections of the skin, kidneys, bladder or prostate.  It is a very popular antibiotic that has a remarkable action, excellent tissue penetration and least possible side effects. This medication is available in ophthalmic solution. It can be applied directly into your eyes and treat bacterial infection.  

It is effective against various bacteria, listed as E.Coli, H.influenza, Klebsiella Pneumonia, Legionella pneumonia, Staphylococcus epidermis, Staphylococcus epidermis, Streptococcus pyogenes, Mycoplasma Pneumonia. This solution is used for the treatment of conjunctivitis.

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) Usage

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) is an antibiotic belongs to a quinolone family of medicines known for treating a bacterial infection. This drug is indicated for the treatment of bacterial eye infections like Bacterial Conjunctivitis.

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) works?

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) belongs to class of fluoroquinolone broad spectrum antibiotic that active against gram positive and gram negative bacteria and stops the formation of bacterial DNA by hindering its cell division process. It impacts upon DNA gyrase enzyme and stops the separation of bacterial DNA. In this way, it stops the formation of bacterial DNA and causes demise of bacteria. 

Don’t apply this solution if you have any allergy to the Norflox (Norfloxacin 0.3% (5 ml) Eye Drop), have fungal infection, have viral infection, are pregnant or planning to become pregnant, you are breast feeding.

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) Dosage information

Take Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) as per your doctor’s direction and refer the medicine leaflet to know more details about this drug. The general way of using Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) is as follows: Always wash your hands before using the eye drops. After that, bend your head backward and pull down your eyelid down. Hold the dropper above one eye. Allow the drops to go eyelid and keep the eye closed for 2 to 3 minutes. Repeat the same for second eye. Strictly prohibit the use of eye drops when you are wearing contact lenses. Don’t touch the eye dropper with your hands, eyes and eyelids.

Take the medicine exactly as your doctor prescribed. The time period of the dose depends on the individual’s condition like what you are being treated for and what are your doctor’s recommendations. Don’t discontinue this drug till the doctor tells you to stop it. The longer you use this drug, the positive results you will get.

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) Side effects:

Some of the common side effects of the medicine include:

• Eye burning
• Irritation
• Stinging
• Itching
• Blurred vision
• Redness
• Eyelid itching
• Eyelid swelling
• Sensitivity to light
• Bad taste in your mouth

In case the side effect become serious get in touch with your doctor as soon as you can. This is not a complete list of side effects that may happen. There may be other side effects as well.

Norflox (Norfloxacin 0.3% (5 ml) Eye Drop) Warning:

Things to remember:

• Do not share the medicine with anyone even if the person is suffering from the same symptoms.
• Use the medicine only for the purpose specified and not for any other purpose.
• Store the medicine in a cool and dry pace away from heat, light and moisture.
• Wash your hands properly before use.
• Do not touch the tip of the medicine bottle because it may lead to contamination.
• Wait at least 15 minutes after removing contact lenses and then apply the medicine.
• The medicine may blur your vison. Hence it is best to avoid activity that require high alertness such as operating heavy machinery, driving etc.
• Do not use another eye drop without the consultation of your doctor.
• If the symptoms persist eiven after application of the medicine for substantial period of time then you must get in touch with your doctor again.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contains two active ingredients Lopinavir and Ritonavir.  It is mainly used to treat people with human immunodeficiency virus (HIV) infection. You can buy Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) online also.

This medication is an HIV-1 protease inhibitor which is used in combination with other antiretroviral agents for HIV-1 infection treatment in adults and paediatric patients 14 days and older.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) used for?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over and children over 6 months. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other medications that have a different mechanism of action to the components in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) work?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contain lopinavir and ritonavir, which are both inhibitors of HIV protease and are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). Retroviruses convert RNA to DNA, by the action of the viral-specific enzyme reverse transcriptase (RT). The viral DNA is then integrated into the DNA of infected immune cells so that the virus can replicate. Most of the antiviral activity of Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is due to lopinavir, which is a potent inhibitor of HIV protease, and prevents cleavage of the Gag-Pol polyprotein, an important protein in the development of active virus. The viral protease enzyme cleaves (breaks down) the Gag-Pol polyprotein during final stages of the replication cycle so that fully active mature virus can be released to infect new cells. Inhibition of protease cleavage by Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) results in the production of immature, non-infectious viral particles. Ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is included in the combination not as a protease inhibitor but because it inhibits the CYP3A-mediated metabolism (breakdown in the liver) of lopinavir, thereby increasing the plasma levels of lopinavir so that lopinavir can be used at a lower dose. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other retrovirals that have a different mechanism of action, like emtricitabine and tenofovir, both nucleoside reverse transcriptase inhibitor (NRTI) that work by blocking the action of RT, inhibiting viral replication. The combined action of lopinavir and ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), in conjunction with other retroviral drugs, inhibits the production of active HIV so that the viral load (amount of virus) is reduced. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) Side Effects

• The most common Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) side effects occurring in 5% or more of the patients undergoing treatment with this medication were diarrhea, nausea, abdominal pain, asthenia, vomiting, headache, and dyspepsia.
• The most commonly reported Generic Kaletra side effects of moderate severity that are thought to be drug related are: abdominal pain, abnormal stools (bowel movements), diarrhea, feeling tired, headache, and nausea. Children taking this medicine may sometimes get a skin rash.
• Blood tests in patients taking this medicine may show possible liver problems. People with liver disease such as Hepatitis B and Hepatitis C who take this medicine may have worsening liver disease. Liver problems including death have occurred in patients taking this medicine. In studies, it is unclear if this medicine caused these liver problems because some patients had other illnesses or were taking other medicines.
• Some patients taking this medicine can develop serious problems with their pancreas (pancreatitis), which may cause death. You have a higher chance of having pancreatitis if you have had it before. Tell your doctor if you have nausea, vomiting, or abdominal pain. These may be signs of pancreatitis.
• Some patients have large increases in triglycerides and cholesterol. The long-term chance of getting complications such as heart attacks or stroke due to increases in triglycerides and cholesterol caused by protease inhibitors is not known at this time.
• Diabetes and high blood sugar (hyperglycemia) occur in patients taking protease inhibitors such as this medicine. Some patients had diabetes before starting protease inhibitors, others did not. Some patients need changes in their diabetes medicine. Others needed new diabetes medicine.
• Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.
• Some patients with hemophilia have increased bleeding with protease inhibitors. There have been other side effects in patients taking this medicine. However, these side effects may have been due to other medicines that patients were taking or to the illness itself. Some of these side effects can be serious. If you suspect that you took more than the prescribed dose of this medicine, contact your local poison control center or emergency room immediately. As with all prescription medicines, this medicine should be kept out of the reach of young children.

What medications interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)?

Always inform your physician about the drugs you are taking till date. Provide complete list of prescription or non prescription drugs and any other disease. This way, your physician will assist you with the list of medicine and other things that may interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets).

Warnings & Precautions When Using Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

• Do not take this medicine if you have had a serious allergic reaction to Lopinavir or Ritonavir (the active ingredients).
• This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby.
• You should tell your doctor if you have liver problems or are infected with Hepatitis B or Hepatitis C.
• Some people taking protease inhibitors develop new or more serious diabetes or high blood sugar. Be sure to tell your doctor if you have diabetes or an increase in thirst and/or frequent urination. Some people with hemophilia have had increased bleeding. It is not known whether the protease inhibitors caused these problems. Be sure to tell your doctor if you have hemophilia types A and B. Together with your doctor, you need to decide whether this medicine is right for you.
• Do not take this medicine if you are taking certain other medicines. These could cause serious side effects that could cause death. Before you take this medicine, you must tell your doctor about all the medicines you are taking or are planning to take.

Zidovir (Zidovudine 100mg Capsule)

Zidovir (Zidovudine 100mg Capsule) contains Zidovudine as an active ingredient. Zidovudine belongs to a class of nucleoside reverse-transcriptase inhibitor (NRTI). It is a blood brain barrier permeable. Zidovudine is an antiretroviral medicine used to treat HIV infection. It is used along with other HIV medications to treat HIV.

What is Zidovir (Zidovudine 100mg Capsule) used for?

Zidovir (Zidovudine 100mg Capsule) is given to patients who suffer from HIV to treat and control their infection, and to reduce the risk of other HIV related illnesses. This drug is a type of nucleoside reverse transcriptase inhibitor, or NRTI, which works by slowing down the spread of HIV in the body. Apart from the above mentioned uses, this drug is also sometimes given to pregnant women with HIV to prevent it being passed to an unborn baby, or to prevent infection in somebody who has come into contact with the virus.

How to Zidovir (Zidovudine 100mg Capsule)  use

Take Zidovir (Zidovudine 100mg Capsule) by mouth 2 to 3 times a day with or with out food as directed by your doctor. Do not miss the dose as drug should be maintained at constant level for better treatment.

How does Zidovir (Zidovudine 100mg Capsule) work?

Zidovir (Zidovudine 100mg Capsule)Zidovir (Zidovudine 100mg Capsule) works by blocking an HIV enzyme called, HIV reverse transcriptase. By doing this, it prevents HIV from replicating and decreases the amount of HIV in the blood.

Working of the drug:

Zidovudine is a nucleoside reverse transcriptase inhibitors (ntris) drug that works by blocking the enzyme called reverse transcriptase. This enzyme is an essential part of replication mechanism of HIV and thus, the drug reduces the amount of infectious virus in the body.

How should Zidovir (Zidovudine 100mg Capsule) be taken?

• Zidovir (Zidovudine 100mg Capsule) comes in the form of a capsule. Taking Zidovir (Zidovudine 100mg Capsule), with a glass of water will help you to swallow it.
• To treat HIV infection in adults: The usual dose of Zidovir (Zidovudine 100mg Capsule) is 600 mg/ day, and it should be taken in divided doses. It is to be taken together with other antiretrovirals agents.
• To treat HIV in pediatrics who aged 4 -<18 years, the dosage regimen is based upon the body weight. Your doctor will prescribe this medicine according to the weight of your child. Alternatively, treatment with Zidovir (Zidovudine 100mg Capsule) may also be based on body surface area for every child. The usual dose is of Zidovudine is 480mg/m2 in divided doses (240 mg/m2 two times a day or 160 mg/m2 three times a day).
• For the prevention of mother-to-child  HIV-1 transmission:

Maternal Dosing- The usual dose of Zidovir (Zidovudine 100mg Capsule) is 100 mg five times a day, until the labor start. During labor and delivery, 2mg/kg of the medicine should be administered intravenously over one hour followed by 1 mg/kg/hour until clamping of the navel string.

Neonatal Dosing: The usual dose of Zidovir (Zidovudine 100mg Capsule) is 2 mg/kg every 6 hours starting within twelve hours after the birth of a child, and the treatment should be continued for 6 weeks of age. In neonates, Zidovir (Zidovudine 100mg Capsule) should be administered intravenously at 1.5 mg/kg, infused over 30 minutes every six hours.

• Do not take more or less amount of capsule than your doctor has prescribed.
• Do not stop taking the capsules without asking your doctor.
• Take the medicine continuously as long as your doctor recommends you. Zidovir (Zidovudine 100mg Capsule) is a drug that prevents further damage caused by the HIV, but it does not cure your condition. You should not stop taking the drug and continue taking it, even if you feel better. Because stopping the intake of the drug may reverse your improving condition.
• Overdose: If you accidently take an extra capsule, call your doctor or hospital casualty department immediately.

Zidovir (Zidovudine 100mg Capsule) Overdose:

If you feel any frightening symptoms, then immediately call the doctor and inform him about the possible side effects of over dosage. If the situation worsens then visit the nearest healthcare center or call the emergency helpline number.

Zidovir (Zidovudine 100mg Capsule) Miss dose:

In case you forget to take the dose, skip the dose and take the next dose on the recommended time period. Do not double up the dose for the missed one.

What are Side effects of Zidovir (Zidovudine 100mg Capsule)?

Like all drugs, Zidovir (Zidovudine 100mg Capsule) can cause side-effects although, not everyone gets them. Contact your doctor, if any of the following symptoms appear:

• Constipation
• Nausea
• Diarrhea
• Blurred vision
• Vomiting
• Constipation
• Headache

Some side effects of Zidovir (Zidovudine 100mg Capsule) can be serious. Call your doctor immediately, if you experience:

• Chills
• Numbness, tingling or burning sensation
• Liver problems
• Skin rashes
• Hives

The side effects that are mentioned above are not the only ones that you may experience due to Zidovir (Zidovudine 100mg Capsule). If you get any serious adverse effects due to Zidovir (Zidovudine 100mg Capsule), call your doctor right away.

What medications interact with Zidovir (Zidovudine 100mg Capsule)?

The following medicines should be avoided, in case doctor recommends you Zidovir (Zidovudine 100mg Capsule) to avoid possible drug interactions.

• Ganciclovir
• Rifampicin
• Doxorubicin
• Sulfa drugs
• Lamivudine
• Sulfa drugs

What is Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets)?

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) containing the 2 active ingredients tenofovir disoproxil fumarate and emtricitabine is considered a nucleoside reverse transcriptase inhibitors (NRTIs) type of medication. The medication works by controlling and preventing the HIV cells from multiplying in the body to help the immune system work better. It should be used in combination with other medications to lower the chance of suffering from HIV complications and slowing the progression of the disease from HIV to AIDS. Using more than 1 type of medication can prevent the body from becoming immune to the treatment.

What is Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) used for?

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over age 18. Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) are used combination with other medications that have a different mechanism of action to the components in Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets), and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4 cell numbers, so that the immune system can recover, reducing the risk of disease progression.

 How does Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) work?

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) contain a combination of two antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate, which are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Emtricitabine and tenofovir disoproxil fumarate are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Emtricitabine is an analogue of cytidine and tenofovir is an analogue of adenosine. The combined action of these two antiiretroviral drugs in Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) prevents the integration of the virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus). Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Tenvir-EM Adverse effects

Patients using Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) may encounter unwanted side effects such as:

• Nausea
• Vomiting
• Diarrhea
• Headaches
• Dizziness
• Strange dreams
• Stomach pain
• Insomnia

Contact a doctor immediately should side effects persist or encounter more severe side effects such as:

• Irregular heartbeat
• Tremors
• Joint pain
• Severe lower back pain
• Signs of new infections
• Unexplained weight loss
• Signs of overactive thyroid
• Mental or mood changes

Tenvir-EM Dosage and Administration

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) should be taken strictly in accordance with the prescription given to you by your physician or pharmacist. The dosage varies from case to case, but most often it is one tablet taken once a day with some water with or without food. Do not discontinue or change the dosage of the medication without checking with your doctor first.

 Precautions

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) can be harmful for patients suffering from existing medical conditions like hepatitis B, bone, liver or kidney disease. If you suffer from an existing medical condition, you will have to be monitored closely while you are on this treatment. Therefore it is advisable that your physician has your complete medical history prior to starting the medication. Your physician will also need to know if you are

• Allergic to any medication
• You are currently taking any medication, supplement and vitamins
• You are breastfeeding, pregnant or trying to conceive
• You are having any herbal supplements

Please inform your physician if you currently have any existing allergic conditions. It is also advisable to seek a doctor’s consultation if you feel that you may have an adverse reaction to the medication.

 Warnings

Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.

Tenvir-EM (Tenofovir Disoproxil Fumarate 300mg, Emtricitabine 200mg Tablets) is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.

The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets)

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) are indicated for the treatment of hiv-1 infection in adults. It is recommended that Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) be taken on an empty stomach, preferably at bedtime. Bedtime dosing may improve the tolerability of nervous system symptoms associated with efavirenz. The increased efavirenz concentrations observed following administration of efavirenz with food may lead to an increase in the frequency of adverse events. Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) are not indicated for use in pediatric patients.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) is a combination of tenofovir, lamivudine, and efavirenz to treat hiv infected people. Each film-coated tablet contains 600 mg of efavirenz, 300 mg of lamivudine and another 300 mg of tenofovir disoproxil fumarate. It can be taken alone and with combination of other medications. This medication helps to control the hiv infection and help to improve the quality of life. In additions, it lowers the risk to get hiv complications like new infections, cancer. It does not cure the infection perfectly, but somehow prevent the spread to others through sexual contact or blood contamination, including sharing the needles.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) Uses

Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children and also used in the treatment of Hepatitis B virus infection.

How it Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) works

Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells). It does not cure HIV completely but reduces the chances of getting acquired immunodeficiency syndrome (AIDS) and HIV related infections or cancer.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) Contraindications:

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) is contraindicated in patients with hypersensitive to any of the components of the product. It should not be administered concurrently with astemizole, bepridil, cisapride, midazolam, pimozide, and triazolam or ergot derivatives. It is because for cyp3a4 as efavirenz could result in the inhibition of the metabolism of this medication and can create a serious life threatening adverse events, including cardiac arrhythmias, prolonged sedation, or respiratory depression. Again it should not be administered concurrently with voriconazole as it is significantly decreased voriconazole plasma concentrations.

This medication is dangerously contraindicated with amprenavir, fosamprenavir, calcium, atazanavir, indinavir, lopinavir, ritonavir, saquinavir, warfarin, carbamazepine, phenytoin, phenobarbital, setailine, itraconazole, ketoconazole, clarithromycin, rifampin, rifabutin, avorvastin, paravastin, simvastatin, methadone, ethinyl estradiol, ditiazem.

It is better to tell your doctor before medication and be frank if you take any other medication, including all the prescription and non-prescription medications, also if you take vitamins and other herbal products.

Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) Dosage and Administrations:

One tablet once a day is the recommended dosage of Trioday (Tenofovir Disoproxil Fumarate 300mg, Lamivudine 300mg, Efavirenz 600mg Tablets) medicine. It can be taken on an empty stomach for the best result most preferably at bedtime because during this time it may improve the tolerability of nervous system symptoms associated with efavirenz. Administration of this medicine with a high-fat meal increased the mean AUC and Cmax of efavirenz by 28% and 79% respectively, and in combination of Tenofovir and lamivudine with a high-fat meal or a light meal increased the mean AUC and Cmax of Tenofovir by 35% and 15% respectively and it does not affect Lamivudine exposures.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Introduction

Dinex EC (Didanosine Delayed - Release 400mg Capsules) is an oral antiretroviral agent which is active against HIV infection. This drug is a synthetic purine derivative and similar to stavudine and zidovudine which inhibits the reverse transcriptase enzyme. The drug blocks reproduction of the human immunodeficiency virus which affects people causing AIDS. It inhibits replication of HIV by preventing DNA replication. It is used in combination with other antiretroviral drugs in the treatment of HIV infection and AIDS.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Use

This drug is known to be used as treatment to HIV infection and postexposure prevention following occupational or nonoccupational exposure to HIV with other antiretrovirals.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Dosage and administration

The recommended total daily dose is based on body weight and administered as one capsule given once a day. The recommended total daily dose of pediatric patients with a weight of less than 20 kg and who can swallow is based on body weight. The initial dose is 250 mg while doctor may also increase the dose up to 400 mg. Doses may be taken in 1 to 2 divided doses. In infants, dose is 50 to 100 mg/m2 twice daily.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Important Precautions

Give drug on an empty stomach at least 30 minutes before or 2 hours after meals to avoid decreasing the absorption. IF pancreatitis is suspected, stop giving the drug and don't continue until pancreatitis is ruled out. Adequate hydration is required unless instructed to restrict fluid intake. Inform those with preexisting liver dysfunction that hepatoxicity may result due to therapy. Inform physician if you have a kidney disease, since you may need a lower dosage. Take drug at exact prescribed timing since missing doses may increase the chance of virus becoming resistant to HIV medications.

Dinex EC (Didanosine Delayed - Release 400mg Capsules) Side effects

The common side effects of the drug are nausea, vomiting, diarrhea or changes in body fat. Report immediately if there are instances of any loss of sensation, numbness, or tingling in fingers, toes or feet; persistent unresolved abdominal distress, changes in vision, or signs of infection such as burning on urination, perineal itching, and white plaques in mouth, unhealed sores, persistent sore throat and cough. Adverse reactions may also occur such as aggressive reaction, allergic reaction, convulsion, liver failure and neuropathy.

Other important Information on Dinex Ec Capsule

Missing a dose

In case you miss a dose, take it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not take extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Overdosage of Dinex EC (Didanosine Delayed - Release 400mg Capsules)

Do not take more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side effects. If you suspect that you or anyone else who may have overdosed of Dinex EC (Didanosine Delayed - Release 400mg Capsules), please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.

Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.

Storage of Dinex EC (Didanosine Delayed - Release 400mg Capsules)

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Dinex EC (Didanosine Delayed - Release 400mg Capsules).

Expired Dinex EC (Didanosine Delayed - Release 400mg Capsules)

Taking a single dose of expired Dinex EC (Didanosine Delayed - Release 400mg Capsules) is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to take expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.

What is Dinex EC (Didanosine Delayed - Release 250mg Capsules)?

Dinex EC (Didanosine Delayed - Release 250mg Capsules) is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body. Dinex EC (Didanosine Delayed - Release 250mg Capsules) is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Dinex EC (Didanosine Delayed - Release 250mg Capsules) is not a cure for HIV or AIDS. Dinex EC (Didanosine Delayed - Release 250mg Capsules) may also be used for purposes not listed in Dinex EC (Didanosine Delayed - Release 250mg Capsules) guide. Overdose symptoms may include some of the serious side effects listed in Dinex EC (Didanosine Delayed - Release 250mg Capsules) guide.

Pancreatitis

Fatal and non-fatal pancreatitis has occurred during therapy with did anosine used alone or in combination regimens in both treatment-naïve and treatment-experienced patients, regardless of degree of immunosuppression.  Dinex EC (Didanosine Delayed - Release 250mg Capsules)should be suspended in patients with signs or symptoms of pancreatitis. Patients treated with Dinex EC (Didanosine Delayed - Release 250mg Capsules) in combination with stavudine, with or without hydroxyurea, may be at increased risk for pancreatitits.

When treatment with life-sustaining drugs known to cause pancreatic toxicity is required, suspension of didanosine therapy is recommended. In patients with risk factors for pancreatitis, Dinex EC (Didanosine Delayed - Release 250mg Capsules) should be used with extreme caution and only if clearly indicated.  Patients with advanced hiv-1 infection, especially the elderly, are at increased risk of pancreatitis and should be followed closely. Patients with renal impairment may be at greater risk for pancreatitis if treated without dose adjustment.the frequency of pancreatitis is dose-related.

Lactic acidosis/Severe Hepatomegaly with Steatosis

Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including didanosine and other antiretrovirals. A majority of these have been in women. Obesity and prolonged nucleoside exposure may be risk factors. Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk (see warnings and precautions, pregnancy).particular caution should be exercised when administering didanosine to any patient with known risk factors for liver disease; however, cases have also been reported in patients with no known risk factors. Treatment with Dinex EC (Didanosine Delayed - Release 250mg Capsules) should be suspended in any patient who develops clinical signs or symptoms with or without laboratory findings consistent with symptomatic hyperlactatemia, lactic acidosis, or pronounced hepatoxicity (which may include hepatomegaly and steatosis even in the absence of marked transaminase elevations).

Hepatic Toxicity

The safety and efficacy of Dinex EC (Didanosine Delayed - Release 250mg Capsules) have not been established in hiv-infected patients with significant underlying liver disease. During combination antiretroviral therapy, patients with pre-existing liver dysfunction, including chronic active hepatitis, have an increased frequency of liver function abnormalities, including severe and potentially fatal hepatic adverse events, and should be monitored according to standard practice. If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.

Hepatotoxicity and hepatic failure resulting in death were reported during postmarketing surveillance in hiv-infected patients treated with hydroxyurea and other antiretroviral agents.  Fatal hepatic events were reported most often in patients treated with the combination of hydroxyurea, didanosine and stavudine. This combination should be avoided.

Non-cirrhotic Portal Hypertension

Postmarketing cases of non-cirrhotic portal hypertension have been reported, including cases leading to liver transplantation or death. Cases of didanosine-associated non-cirrhotic portal hypertension were confirmed by liver biopsy in patients with no evidence of viral hepatitis.  Onset of signs and symptoms ranged from months to years after start of didanosine therapy. Common presenting features included elevated liver enzymes, esophageal varices, hematemesis, ascites, and splenomegaly.

Patients receiving Dinex EC (Didanosine Delayed - Release 250mg Capsules) should be monitored for early signs of portal hypertension (eg, thrombocytopenia and splenomegaly) during routine medical visits. Appropriate laboratory testing including liver enzymes, serum bilirubin, albumin, complete blood count, and international normalized ratio (inr) and ultrasonography should be considered. Dinex EC (Didanosine Delayed - Release 250mg Capsules)(Didanosine Delayed - Release 250mg Capsules)should be discontinued in patients with evidence of non-cirrhotic portal hypertension.

Immune Reconstitution Syndrome

Immune reconstitution syndrome has been reported in patients treated with combination antiretroviral therapy, including Dinex EC (Didanosine Delayed - Release 250mg Capsules). During the initial phase of combination antiretroviral treatment, patients whose immune system responds may develop an inflammatory response to indolent or residual opportunistic infections (such as mycobacterium avium infection, cytomegalovirus, pneumocystis jirovecii pneumonia , or tuberculosis), which may necessitate further evaluation and treatment.

Autoimmune disorders (such as graves’ disease, polymyositis, and guillain-barré syndrome) have also been reported to occur in the setting of immune reconstitution; however, the time to onset is more variable, and can occur many months after initiation of treatment.

Pregnancy

Pregnancy Category B:

Reproduction studies have been performed in rats and rabbits at doses up to 12 and 14.2 times the estimated human exposure (based upon plasma levels), respectively, and have revealed no evidence of impaired fertility or harm to the fetus due to didanosine. At approximately 12 times the estimated human exposure, didanosine was slightly toxic to female rats and their pups during mid- and late-lactation. These rats showed reduced food intake and body weight gains but the physical and functional development of the offspring was not impaired and there were no major changes in the f2 generation. A study in rats showed that didanosine and/or its metabolites are transferred to the fetus through the placenta. Animal reproduction studies are not always predictive of human response.

There are no adequate and well-controlled studies of didanosine in pregnant women. Didanosine should be used during pregnancy only if the potential benefit justifies the potential risk.

Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. It is unclear if pregnancy augments the risk of lactic acidosis/hepatic steatosis syndrome reported in non-pregnant individuals receiving nucleoside analogs (see warnings and precautions). The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk. Healthcare providers caring for hiv-infected pregnant women receiving didanosine should be alert for an early diagnosis of lactic acidosis/hepatic steatosis syndrome.

Pediatric Use

Use of didanosine in pediatric patients from 2 weeks of age through adolescence is supported by evidence from adequate and well-controlled studies of didanosine in adult and pediatric patients (seedosage and administration; undesirable effects; pharmacology). Additional pharmacokinetic studies in pediatric patients support the use of didanosinein pediatric patients who weigh at least 20 kg.

Geriatric Use

In an expanded access program using a buffered formulation of didanosine for the treatment of advanced hiv infection, patients aged 65 years and older had a higher frequency of pancreatitis (10%) than younger patients (5%) (see warnings and precautions). Clinical studies of didanosine, including those for Dinex EC (Didanosine Delayed - Release 250mg Capsules), did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently than younger subjects. Didanosine is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection. In addition, renal function should be monitored and dosage adjustments should be made accordingly (see dosage and administration).

Overdosage

There is no known antidote for didanosine overdosage.  In phase 1 studies, in which buffered formulations of didanosine were initially administered at doses ten times the currently recommended dose, toxicities included:pancreatitis, peripheral neuropathy, diarrhea, hyperuricemia, and hepatic dysfunction. Didanosine is not dialyzable by peritoneal dialysis, although there is some clearance by hemodialysis

Dinex EC (Didanosine Delayed - Release 250mg Capsules) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Dinex EC (Didanosine Delayed - Release 250mg Capsules) may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

• Muscle pain or weakness.
• Numb or cold feeling in your arms and legs.
• Trouble breathing; feeling dizzy, light-headed, tired, or very weak.
• Stomach pain, nausea with vomiting.
• Fast or uneven heart rate.

Stop using Dinex EC (Didanosine Delayed - Release 250mg Capsules) and call your doctor at once if you have any of these other serious side effects:

• Signs of a new infection such as flu symptoms, easy bruising or unusual bleeding, loss of appetite, mouth sores.
• Severe pain in your upper stomach spreading to your back, nausea and vomiting; itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• Swelling around your stomach, feeling of fullness, feeling short of breath, coughing up blood;
• Numbness, tingling, or pain in your hands or feet.
• Pain in one or both eyes, vision problems, seeing flashes of light.
• Pale skin, easy bruising or bleeding, feeling light-headed, rapid heart rate, trouble concentrating.
• Increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia).
• Diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex.
• Swelling in your neck or throat (enlarged thyroid).
• weakness or prickly feeling in your fingers or toes.
• Problems with walking, breathing, speech, swallowing, or eye movement.
• severe lower back pain, loss of bladder or bowel control.

 Less serious side effects  may include:

• Mild skin rash;
• Diarrhea; headache;
• Changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Capegard (Capecitabine 500mg Tablets)

Capegard (Capecitabine) is a cancer drug which is indicated for colorectal cancer and metastatic breast cancer. Its mechanism of action involves working within the cancer cells to affect their growth. This chemotherapy drug is used for adjuvant treatment for patients affected by Dukes` C colon cancer and as a first line therapy for metastatic colorectal cancer. When used for breast cancer, it may either be used together with other medicines (such as docetaxel) or on its own.

This medicine is classified as an antimetabolite, and it is a prodrug. This means that it is converted into 5-fluorouracil (5-FU) by enzymes in the body. Following this, healthy and tumor cells further convert it into other metabolites (FdUMP and FUTP) that interfere with the process in which DNA, RNA and protein are synthesized. Without DNA, the division and growth of cancerous cells is affected and they are unable to grow properly. This results in their eventual death, allowing for the size of the tumor to be reduced and the growth of the cancer cells stopped.

In addition to attacking cancer cells, this medicine may also affect healthy cells. This could result to side effects. However, due to the fact that the conversion of the prodrug into its active form (5-HU) usually only occurs in the cancerous cells, the risk of side effects is less when compared to other cancer medicines. A significant amount of medical research has been conducted which focused on this medicine`s effects if used for other conditions. These studies examined its effects if used for gastric, pancreatic or esophageal cancer.

How is Capegard (Capecitabine 500mg Tablets) used?

Capegard-500 is usually taken twice daily, in the morning and evening or as directed by a doctor. The tablets should be taken within 30 minutes of a meal along with a full glass of water. The usual cycle of using the drug is every day for 2 weeks, then stopped for 1 week. The tablets should be swallowed whole and not split, chewed or crushed. Contact a doctor for the amount of times needed to repeat the cycle as it will depend on the patient's condition and their response to the therapy.

Side effects

Treatment with the chemotherapy agent Capegard (Capecitabine) can cause side effects. Ensure that you report all reactions to your physician. Possible reactions include:

• Pruritis
• Hair loss
• Low appetite
• Irritated eyes
• Altered taste sensation

Certain adverse events are serious and you will need immediate treatment if they occur. Consult your physician straight away if you suffer from diarrhea, nausea, inflammation of the feet and hands, pain and sores on the mouth, symptoms of an infection or any other severe reactions that have not been referenced in this paragraph.

Dosage  

Capegard (Capecitabine) 500mg tablets are taken by mouth. The dosage needed will be decided upon by the physician in charge of medical care and the patient will need close medical supervision throughout the entire duration of treatment. These tablets need to be swallowed whole alongside a full glass of water within 30 minutes of consuming a meal.

If used for monotherapy, it is possible that treatment will consist of twice daily dosing for a period of 2 weeks, after which a 1 week break will be advised. This 3 week cycle may need to be repeated as necessary in accordance with the instructions of your physician. Patients with renal impairment may need a lower dosage, and it is also important to note that the exact dosage needed may be individualized by the physician based on other factors.

Zidovir (Zidovudine 300mg Tablets)

Zidovir (Zidovudine 300mg Tablets), also sold under the brands Retrovir and Zidovir among several other trade names, is an antiviral drug. This medication belongs to a group of HIV medicines called reverse transcriptase inhibitors that prevent the HIV virus from reproducing in the body.

Zidovir (Zidovudine 300mg Tablets) is prescribed for the treatment of HIV that causes the disease called acquired immunodeficiency syndrome or AIDS. However, this medication will not cure the body of HIV or AIDS. This medication may also be given for conditions not mentioned here.

Important Information about Zidovir (Zidovudine 300mg Tablets)

Do not take Zidovir (Zidovudine 300mg Tablets) antiviral HIV medicine (Retrovir, Zidovir) if you have a known allergy to it or any medicine that has Zidovir (Zidovudine 300mg Tablets). Also do not take Zidovir (Zidovudine 300mg Tablets) with other medicines that also contain Zidovir (Zidovudine 300mg Tablets) or Stavudine.

Lactic acidosis has been observed in some people who took Zidovir (Zidovudine 300mg Tablets). Initial symptoms of lactic acidosis may deteriorate over time and can prove fatal. Hence you must get medical attention right away on first signs of lactic acidosis such as muscle pain or weakness, numb or cold feeling in the limbs, breathing trouble, stomach pain, or nausea with vomiting.

Zidovir (Zidovudine 300mg Tablets) can also cause severe and life threatening damage to your liver. Let your doctor know in advance if you have a condition affecting liver, especially Hepatitis C. Seek medical attention right away if you have any of the following symptoms of liver damage: sever pain in upper stomach which advances to the back, nausea and vomiting, fast heartbeats, itching, loss of appetite, dark urine, clay colored stools, or jaundice.

Zidovir (Zidovudine 300mg Tablets) can lower the count of white blood cells, the component of blood that helps the body to fight infections. You must take necessary precautions to avoid getting infected such as not being near sick people or avoiding activities that increases the risk of bleeding. Let your doctor know right away if you get any signs of an infection while taking this medication.

Lamivudine is an FDA pregnancy category C drug. It is not known if it can harm an unborn baby if taken while being pregnant. HIV can be transmitted to your baby if you are not treated properly during pregnancy.

Zidovir (Zidovudine 300mg Tablets) Uses

Zidovir (Zidovudine 300mg Tablets) is classified as a nucleoside analog, and it treats HIV infections by inhibiting viral reverse transcriptase and DNA polymerases. The HIV virus needs to replicate its DNA in order to spread and infect more cells. An enzyme called RT (reverse transcriptase) is needed for this to take place, and by blocking RT, this medicine helps to terminate the DNA chain and prevent the virus from multiplying. Improvements in the clinical condition of patients can thereby be achieved. Some researchers have studied it for HIV prevention (prophylaxis).

How should I take Zidovir (Zidovudine 300mg Tablets)?

Take Zidovir (Zidovudine 300mg Tablets) HIV/AIDS medication (Retrovir, Zidovir) strictly according to your doctor’s direction or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so. Also, do not take this medication after the prescribed period is over. All medications come with a patient leaflet. Refer the instructions in them for detailed information on that particular medication.

HIV/AIDS is usually treated with a combination of drugs. Always take the prescribed drugs as directed by your doctor. Store this medication in a cool and dry place. Always store Zidovir (Zidovudine 300mg Tablets) in a cool and dry place.

Zidovir (Zidovudine 300mg Tablets) Side Effects

• Some common side effects of Zidovir (Zidovudine 300mg Tablets) are nausea, headache, vomiting, dizziness, drowsiness, or diarrhea. If any of these effects persist or deteriorate, seek medical attention right away.
• Some people may experience a deteriorating of a previous medical condition as their immune system recovers, or develop new conditions due to overactive immune system. Let your doctor know right away if you develop any new condition or any of you existing conditions worsen.
• Lactic acidosis has been observed in some people who took Zidovir (Zidovudine 300mg Tablets). Initial symptoms of lactic acidosis may deteriorate over time and can prove fatal. Hence you must get medical attention right away on first signs of lactic acidosis such as muscle pain or weakness, numb or cold feeling in the limbs, breathing trouble, stomach pain, or nausea with vomiting.
• Zidovir (Zidovudine 300mg Tablets) can also cause severe or life threatening damage to your liver. Seek medical attention right away if you have any of the following symptoms of liver or pancreas damage: sever pain in upper stomach which advances to the back, nausea and vomiting, fast heartbeats, itching, loss of appetite, dark urine, clay colored stools, or jaundice.
• The side effects mentioned above are not the only ones that you may experience or witness due to Zidovir (Zidovudine 300mg Tablets). If you get any serious side effects due to this medication, contact your doctor right away.

Zidovir (Zidovudine 300mg Tablets) Dosing Information

Zidovir (Zidovudine 300mg Tablets) dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly. Remember to follow your doctor’s advice properly for best results.

What is Efavir (Efavirenz 600mg Tablets)?

Efavir (Efavirenz 600mg Tablets) containing the active ingredient efavirenz belongs to a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). The medication works by decreasing the amount of HIV in the body and preventing the cells from multiplying to allow the immune system to work better. It must be used along with other medications to decrease the chance of developing acquired immunodeficiency syndrome (AIDS) and HIV related illnesses such as serious infections or cancer.

How does Efavir (Efavirenz 600mg Tablets) work?

Efavir (Efavirenz 600mg Tablets) (also known as Sustiva) contain efavirenz, a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), which is only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Efavirenz in Efavir (Efavirenz 600mg Tablets) acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA. This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus). Efavir (Efavirenz 600mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

When should Efavir (Efavirenz 600mg Tablets) not be used?

You should not use Efavir (Efavirenz 600mg Tablets) if you:

• are allergic to efavirenz or any ingredients in Efavir (Efavirenz 600mg Tablets)
• are pregnant or are breastfeeding
• have liver disease
• are using Efavir (Efavirenz 600mg Tablets) as a single treatment as it is intended for use only as part of combination therapy
• are taking medicines that interact with Efavir (Efavirenz 600mg Tablets), including: other antiretrovirals, such as, amprenavir, indinavir, atazanavir, ritonavir, saquinavir, the antibiotics rifampicin, rifabutin and clarithromycin, the antifungals voriconazole and itraconazole, cholesterol lowering statins like simvastatin and atorvastatin, the antiepileptic carbamazepine, oestrogen containing oral contraceptives, methadone for opioid dependence, the dietary supplement St. John's Wort, the antidepressant sertraline, calcium channel blockers like diltiazem for angina and hypertension, the antihistamine terfenadine, cisapride for reflux, triazolam for anxiety, the sedative midazolam, ergot derivatives for migraine, the antipsychotic pimozide, bepridil for angina

How should Efavir (Efavirenz 600mg Tablets) be taken?

You should take your Efavir (Efavirenz 600mg Tablets) swallowed whole with a glass of water without food, once a day preferably on an empty stomach at bedtime to reduce problems with side effects.  The dose you take depends on your body weight and your doctor’s recommendation.   You should continue to take your Efavir (Efavirenz 600mg Tablets) regularly for as long as your doctor recommends, and you condition should be monitored. Do not suddenly stop taking your Efavir (Efavirenz 600mg Tablets) as this may increase risk of HIV resistance.

Missed dose of Efavir (Efavirenz 600mg Tablets)

If you miss a dose of Efavir (Efavirenz 600mg Tablets) take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

Efavir (Efavirenz 600mg Tablets) Side effects

Be aware of the possible side effects that Efavir (Efavirenz 600mg Tablets) can cause. Certain reactions are listed here:

• Nausea
• Fatigue
• Vertigo
• Lipodystrophy
• Concentration difficulties

Your physician will regularly conduct various medical assessments so that your condition can be monitored. All side effects (no matter how mild) must be thoroughly reported. Rarely, serious reactions will occur. Should you experience bloody urine, abnormal behavioral disturbances, significant appetite reduction, speech problems, unexplained weigh increases or any other severe side effects, see your physician immediately.

Efavir (Efavirenz 600mg Tablets) Warnings

1. The medication can be used to treat HIV but cannot be used to cure HIV or decrease the risk of transmitting the HIV virus to other people.
2. Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.
3. Efavir (Efavirenz 600mg Tablets) is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.
4. The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.

Stavir (Stavudine 30mg Capsules)

Stavir (Stavudine 30mg Capsules) contains Stavudine as an active medicinal substance. Stavudine is a synthetic nucleoside, analog of deoxythymidine with potent antiretroviral activity. It is used along with other antiretroviral agents to treat human immunodeficiency syndrome or HIV-1 infection. Stavudine is an FDA-approved drug prescribed for the treatment of HIV-1 in infants, children, and adults.

Why is this medication prescribed?

Stavir (Stavudine 30mg Capsules) is used along with other medications to treat human immunodeficiency virus (HIV) infection. Stavir (Stavudine 30mg Capsules) is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although Stavir (Stavudine 30mg Capsules) does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other life-style changes may decrease the risk of transmitting (spreading) the HIV virus to other people.

What is Stavir (Stavudine 30mg Capsules) used for?

Stavir (Stavudine 30mg Capsules) is used to treat Human immunodeficiency syndrome or HIV-1 infection.  HIV is a lentivirus (a subgroup of retrovirus) that causes Acquired Immunodeficiency Syndrome (AIDS).  AIDS is a disease in which progressive failure of the immune system leads to opportunistic infections and cancers to prosper.

How does  Stavir (Stavudine 30mg Capsules)  work?

Stavir (Stavudine 30mg Capsules) works by blocking reverse transcriptase enzyme, preventing HIV-1 infection from multiplying in the body and can reduce the amount of HIV in the body of an infected person.

Missed dose of Stavir (Stavudine 30mg Capsules):

If you have forgotten a dose, take it as soon you remember and go back to your usual dosing schedule. If the time to take the next dose is near, leave the forgotten dose and take the next dose. Do not double up the dose to compensate the missed one.

• Take the capsule for as long as your doctor recommended.

What are Side effects of Stavir (Stavudine 30mg Capsules)?

Like other medicines, Stavir (Stavudine 30mg Capsules) may cause adverse effects. Seek medical attention, in case the following troubles arise:

• Neuropathy
• Vomiting
• Headache
• Diarrhea
• Nausea

Some adverse effects of Stavir (Stavudine 30mg Capsules) can be serious. Visit the doctor immediately, in the following situations.

• Rash
• Difficulty moving your hands and feet
• Burning, tingling, numbness in the hands or feet
• Pain in the hands and feet

When should Stavir (Stavudine 30mg Capsules) not be used?

Tell the doctor before consuming Stavir (Stavudine 30mg Capsules):

• If you are hypersensitive to the medicine, or its components.
• If you are taking alcohol products.
• If you have gallstones.
• If you have ever had problems with your pancreas and kidney diseases.
• If you have or ever had neuropathy.
• The drug may cause dizziness. Do not drive or use machinery, while taking Stavir (Stavudine 30mg Capsules) as these activities may require a high degree of mental attention.
• If you are pregnant or intending to become pregnant. You should discuss the benefits and risks of taking Stavir (Stavudine 30mg Capsules) during pregnancy. Breastfeeding women are advised not to take Stavir (Stavudine 30mg Capsules) as it may pass into breast milk and harm the nursing baby.

Remember the following things, to avoid transmission of HIV infection on to others:

• Avoid sharing needles and other injection equipment with other people.
• Avoid sharing personal things that can have blood fluid on them, like toothbrushes and razors.
• Avoid practicing sex without protection. Do practice safe sex by using polyurethane or latex to decrease the chance of sexual contact with vaginal secretions, semen, and blood.

How should Stavir (Stavudine 30mg Capsules) be taken?

• Stavir (Stavudine 30mg Capsules) comes in the form of a capsule. Swallow the capsule with a glass of water. It may be taken with or without a meal.
• The dosage of the drug is based on the body weight of a patient.
• To treat adults who weigh less than 60 kg: The recommended dose is 30 mg every 12 hours.
• To treat adult patients who weigh at least 60 kg: The recommended dose is 40 mg every 12 hours.
• To treat pediatric patients:

Infants from birth to 13 days old- The recommended dose are 0.5 mg/kg every 12 hours.

An infant who is at least 14 days old and whose weight is less than 30 kg- The recommended dose is 1 mg/kg every 12 hours.

• A paediatric patient whose weight is at least 30 kg: The recommended dosage is adult dosage.
• Take the capsule exactly as prescribed by the doctor. Do not alter the dosage plan.
• Overdose: Seek medical attention immediately, in the case of an overdose of Stavir (Stavudine 30mg Capsules).